PeerJ 2019 02 057() e6273 doi 10.7717/peerj.6273 Abstract Background Low-carbohydrate, high-fat (LCHF) diets are useful for treating a range of health conditions, but there is little research evaluating the degree of...
Read MoreGenome biology 2019 02 1120(1) 30 doi 10.1186/s13059-019-1644-0 Abstract BACKGROUND Alternative splicing is a key regulatory mechanism in eukaryotic cells and increases the effective number of functionally distinct gene...
Read MoreeLife 2019 02 128() doi 10.7554/eLife.40811 Abstract Mutations in coding and non-coding regions of FUS cause amyotrophic lateral sclerosis (ALS). The latter mutations may exert toxicity by increasing FUS accumulation. We show...
Read MoreResuscitation 2014 06 0285(9) 1204-11 doi 10.1016/j.resuscitation.2014.04.029 Abstract Hypothermic cardiac arrest has high mortality and few known prognostic factors. We studied retrospectively 34 victims of accidental...
Read MoreImmunity 2019 01 23() pii 10.1016/j.immuni.2019.01.001 Abstract Non-lymphoid tissues (NLTs) harbor a pool of adaptive immune cells with largely unexplored phenotype and development. We used single-cell RNA-seq to characterize...
Read MoreJournal of clinical medicine 2019 02 078(2) pii 10.3390/jcm8020207 Abstract The immune system acting via cancer immune-surveillance is considered a potential target for improving outcomes among some malignancies. The ability to...
Read MoreGastroenterology 2019 02 06() pii 10.1053/j.gastro.2019.01.261 Abstract BACKGROUND & AIMS In a phase 3 trial (RESORCE), regorafenib increased overall survival compared with placebo in patients with hepatocellular carcinoma...
Read MoreNature communications 2019 02 0810(1) 688 doi 10.1038/s41467-019-08405-9 Abstract Corticosteroids are host-directed drugs with proven beneficial effect on survival of tuberculosis (TB) patients, but their precise mechanisms of...
Read MoreNature communications 2019 02 0810(1) 650 doi 10.1038/s41467-018-08247-x Abstract During wound healing in adult mouse skin, hair follicles and then adipocytes regenerate. Adipocytes regenerate from myofibroblasts, a specialized...
Read MoreThe journals of gerontology. Series A, Biological sciences and medical sciences 72(12) 1595-1606 doi 10.1093/gerona/glx089 Abstract Older men (n = 12) and women (n = 18) 65-80 years of age completed 12 weeks of exercise and took...
Read MoreCell reports 26(6) 1598-1613.e8 pii 10.1016/j.celrep.2019.01.036 Abstract Flaviviruses cause systemic or neurotropic-encephalitic pathology in humans. The flavivirus nonstructural protein 1 (NS1) is a secreted glycoprotein...
Read MoreCell reports 26(6) 1544-1556.e8 pii 10.1016/j.celrep.2019.01.043 Abstract The tripeptide glutathione suppresses the iron-dependent, non-apoptotic cell death process of ferroptosis. How glutathione abundance is regulated in the...
Read MoreFrontiers in genetics 2019 01 229() 712 doi 10.3389/fgene.2018.00712 Abstract Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease and is characterized by the degeneration of upper and lower...
Read MoreCell reports 26(6) 1585-1597.e4 pii 10.1016/j.celrep.2019.01.052 Abstract Spondweni virus (SPOV) is the flavivirus that is most closely related to Zika virus (ZIKV). Although SPOV causes sporadic human infections in Africa,...
Read MoreAdvances in nutrition (Bethesda, Md.) 10(suppl_1) S31-S48 doi 10.1093/advances/nmy037 Abstract The consumption of sugar-free foods is growing because of their low-calorie content and the health concerns about products with high...
Read More
By Ludwig Burger FRANKFURT (Reuters) – Bayer is banking on the mild side effects of its...
Read MoreBy Lisa Rapaport (Reuters Health) – Newborns who don’t get baths right away may be more likely to be exclusively breastfed than infants who get whisked away to be washed soon after delivery, a U.S. study suggests....
Read MoreBy Lisa Rapaport (Reuters Health) – More young men and women are binge-drinking into their mid- and late-20s today than a generation ago, increasing their risk of accidental injuries, deaths and a variety of chronic...
Read MoreBy Carolyn Crist (Reuters Health) – Post-mammogram form letters telling women about dense breasts may be more confusing than helpful if they are difficult to read and understand, researchers say. Thirty U.S. states require...
Read MoreBy Carolyn Crist (Reuters Health) – Hand hygiene compliance among paramedics may be “remarkably low,” according to a study that monitored ambulance workers in Scandinavia and Australia over six months....
Read More
