Clinicopathologic predictors of renal outcomes in light chain cast nephropathy: A multicenter retrospective study.

Mar 12, 2020

Light chain cast nephropathy (LCCN) in multiple myeloma often leads to severe and poorly...

Human Papillomavirus Vaccination in Male and Female Adolescents Before and After Kidney Transplantation: A Pediatric Nephrology Research Consortium Study.

Mar 12, 2020

Kidney transplant (KT) recipients have higher incidence of malignancies, including Human Papillomavirus (HPV)-associated cancers. Thus, HPV vaccines may have an important role in preventing HPV-related disease in this...

Long-term Kidney Transplantation Outcomes Network (APOLLO): Design and Rationale.

Mar 12, 2020

Much of the higher risk for end-stage kidney disease (ESKD) in African American individuals relates to ancestry-specific variation in the apolipoprotein L1 gene (). Relative to kidneys from European American deceased-donors,...

Intensive Home Hemodialysis Survival Comparable to Deceased Donor Kidney Transplantation.

Mar 12, 2020

Kidney transplantation (KT) remains the treatment of choice for end-stage kidney disease (ESKD), but access to transplantation is limited by a disparity between supply and demand for suitable organs. This organ shortfall has...

Nocturnal home hemodialysis in children: Advantages, implementation, and barriers.

Mar 12, 2020

Chronic kidney disease and end-stage renal disease (ESRD) in children are major health concerns worldwide with increasing incidence and prevalence. Renal replacement therapies and kidney transplants have remarkably improved the...

A potential role of neutrophil extracellular traps (NETs) in kidney acute antibody mediated rejection.

Mar 12, 2020

The aim of this study was to evaluate neutrophil extracellular traps (NETs) in kidney transplant recipients (KTR) and their potential involvement in acute antibody-mediated rejection (AAMR).We studied 3 groups: KTR with AAMR...

Narratives of patient participation in haemodialysis.

Mar 12, 2020

To explore how working-age adults experience patient participation in hospital haemodialysis.End-stage kidney disease is a progressive, chronic condition imposing patients with high treatment burdens and low health-related...

Atypical features and de novo heterozygous mutations in two siblings with Cockayne syndrome.

Mar 12, 2020

Cockayne syndrome (CS) is a rare autosomal recessive disorder which displays multiorgan dysfunction, especially within the nervous system including psychomotor retardation, cerebral atrophy, microcephaly, cognitive dysfunction,...

Ultrasound-guided percutaneous peritoneal dialysis catheter insertion using multifunctional bladder paracentesis trocar: A modified percutaneous PD catheter placement technique.

Mar 12, 2020

To evaluate the efficacy and safety of ultrasound-guided percutaneous peritoneal dialysis catheter insertion using multifunctional bladder paracentesis trocar.A retrospective review of 103 ESRD patients receiving percutaneous PD...

Treatment Outcomes of Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitis in Patients Over Age 75 Years: A Meta-Analysis.

Mar 12, 2020

The benefits of treating anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) in...

Kidney Health for Everyone Everywhere – From Prevention to Detection and Equitable Access to Care.

Mar 12, 2020

The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health...

Patient characteristics and outcomes after ruxolitinib discontinuation in patients with myelofibrosis.

Mar 12, 2020

This retrospective analysis evaluates morbidities, outcomes and associated risk factors in patients with myelofibrosis (MF) after ruxolitinib discontinuation, using Truven Health Analytics MarketScan® (TR), Optum™...

CXCR4 expression in the bone marrow microenvironment is required for hematopoietic stem and progenitor cell maintenance and early hematopoietic regeneration after myeloablation.

Mar 12, 2020

The bone marrow microenvironment/niche plays a key role in regulating hematopoietic stem and...

Ruxolitinib for the treatment of steroid-refractory acute GVHD (REACH1): a multicenter, open-label, phase 2 trial.

Mar 12, 2020

Patients who develop steroid-refractory acute graft-versus-host disease (aGVHD) following allogeneic hematopoietic cell transplantation have poor prognosis, highlighting an unmet therapeutic need. In this open-label, phase 2...

Evaluation of Noninvasive Hemoglobin Monitoring in Children with Congenital Heart Diseases.

Mar 12, 2020

Noninvasive measurement of blood hemoglobin could save time and decrease the risk of anemia and infection. The accuracy of Co-oximetry-derived noninvasive hemoglobin (Sp-Hb) had been evaluated in pediatric population; however,...

Congenital dyserythropoiesis anemia type Ia with a novel CDAN1 mutation diagnosed by whole exome sequencing.

Mar 12, 2020

Congenital dyserythropoiesis anemia type Ia (OMIM:224120), is a rare hereditary anemia. The diagnosis is difficult to make and usually delayed in part due to its rarity and nonspecific clinical manifestations.Whole exome...