Fatal overdose prevention and experience with naloxone: A cross-sectional study from a community-based cohort of people who inject drugs in Baltimore, Maryland.

Mar 12, 2020

Overdose is a leading cause of death in the United States, especially among people who inject...

Identification of gp120 polymorphisms in HIV-1 B subtype potentially associated with resistance to fostemsavir.

Mar 12, 2020

We evaluated natural resistance to the new antiretroviral fostemsavir and its potential...

Development and validation of a multiplex UHPLC-MS/MS assay with stable isotopic internal standards for the monitoring of the plasma concentrations of the antiretroviral drugs bictegravir, cabotegravir, doravirine, and rilpivirine in people living with HIV.

Mar 12, 2020

The widespread use of highly active antiretroviral treatments has dramatically changed the...

An ultralong CDRH2 in HCV neutralizing antibody demonstrates structural plasticity of antibodies against E2 glycoprotein.

Mar 12, 2020

A vaccine protective against diverse HCV variants is needed to control the HCV epidemic....

The Cross-Talk Between Gut Microbiota and Lungs in Common Lung Diseases.

Mar 12, 2020

Emerging findings indicate there is a vital cross-talk between gut microbiota and the lungs, which...

The dual phosphodiesterase 3/4 inhibitor RPL554 stimulates rare class III and IV CFTR mutants.

Mar 12, 2020

Over 2,000 mutations have been reported in the gene, many of which cause disease but are rare and...

Airway hyperresponsiveness, remodeling and inflammation in infants with wheeze.

Mar 12, 2020

The relationship of airway hyperresponsiveness to airway remodeling and inflammation in infants...

Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways.

Mar 12, 2020

Tenacious mucus produced by tracheal and bronchial submucosal glands is a defining feature of...

PROGNOSTIC IMPACT OF DIABETES MELLITUS ON OVERALL SURVIVAL IN A NATIONWIDE POPULATION-BASED COHORT OF PATIENTS WITH PANCREATIC CANCER.

Mar 12, 2020

Diabetes mellitus (DM) is a risk factor for pancreatic cancer but its prognostic impact remains...

Treatment of Recurrent Infection in an Immunocompromised Patient with Severe Neutropenia Not Responding to Standard Therapy.

Mar 12, 2020

One of the most effective strategies in reducing the risk of infection (CDI) recurrence is fecal...

A meta-analysis of ABCG2 gene polymorphism and non-small cell lung cancer outcomes.

Mar 12, 2020

We aimed to analyze the correlation between ABCG2 gene polymorphisms of 34 GG/(GA + AA) loci, 421...

Safety and efficacy of first-line dacomitinib in Japanese patients with advanced non-small cell lung cancer.

Mar 12, 2020

In a subgroup of Japanese patients in the ARCHER 1050 randomized phase 3 trial, we evaluated the...

Genetic characterization of the spike gene of porcine epidemic diarrhea viruses (PEDVs) circulating in Vietnam from 2015 to 2016.

Mar 12, 2020

Porcine epidemic diarrhea (PED) is a highly contagious swine disease caused by the PED virus...

Laxative Activity of the Hot-Water Extract Mixture of Thunb. and Mazel in Chronic Constipation Model SD Rats.

Mar 12, 2020

This study examined the laxative effects of hot-water extracts of Thunb. (HD), Mazel (PM), and a...

Protective Effect of Asacol in Combination with Pantoprazole in Ulcerative Colitis Patients Who Defecate Asacol Tablets Intactly: A Clinical Trial Study.

Mar 12, 2020

Mesalazine formulations are the drug of choice in the treatment of ulcerative colitis (UC). They...

PI3KC3 subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation.

Mar 12, 2020

NRBF2, a regulatory subunit of the ATG14-BECN1/Beclin 1-PIK3C3/VPS34 complex, positively regulates...

Clinical Pharmacology of Janus Kinase Inhibitors in Inflammatory Bowel Disease.

Mar 12, 2020

Inflammatory bowel disease, including ulcerative colitis and Crohn’s disease, are chronic...

Upper Gastrointestinal Mucosal Injury Associated with Ticagrelor Plus Aspirin, Ticagrelor Alone, or Aspirin Alone at 1-Year Post-CABG.

Mar 12, 2020

The presence and severity of upper gastrointestinal mucosal lesions have not been evaluated using...

[The state and role of esophagus, stomach, intestinal microbiota in patients with ulcer disease, chronic gastritis, esophagitis.]

Mar 12, 2020

The microflora of 64 biopsies taken during fibrogastroduodenoscopy of the mucous membrane of the...

Generalizability assessment of head and neck cancer NTCP models based on the TRIPOD criteria.

Mar 12, 2020

This review aimed to provide an overview of the level of maturity of normal tissue complication...

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Month: March 2020