Comparative analysis of the dual EGFR-DNA targeting and growth inhibitory properties of 6-mono-alkylamino- and 6,6-dialkylaminoquinazoline-based type II combi-molecules.

Mar 9, 2020

Over the past decade, we described a novel tumour targeted approach that sought to design...

Psychological stress enhances tumor growth and diminishes radiation response in preclinical model of lung cancer.

Mar 9, 2020

Patients with life-threatening illnesses, such as cancer, experience emotional distress. This...

RET isoform-specific interaction with scaffold protein Ezrin promotes cell migration and chemotaxis in lung adenocarcinoma.

Mar 9, 2020

Increased expression of REarranged during Transfection (RET) kinase is reported in 10-20 % of lung...

Microwave ablation for non-small cell lung cancer with synchronous solitary extracranial metastasis.

Mar 9, 2020

Local therapy including surgery or radiotherapy has been reported for the treatment of non-small...

Advances in non-intensive chemotherapy treatment options for adults diagnosed with acute myeloid leukemia.

Mar 9, 2020

Acute myeloid leukemia (AML) is primarily a disease of older adults. Many older patients with AML...

The possible protective effect of Nano-Selenium on the endocrine and exocrine pancreatic functions in a rat model of acute pancreatitis.

Mar 9, 2020

Acute pancreatitis is a serious condition with multi-factorial etiology. The negative impact of...

miR-18a Inhibitor Suppresses Leukemia Cell Proliferation by Upregulation of PTEN Expression.

Mar 9, 2020

BACKGROUND Leukemia is common in aging adults and has very high mortality worldwide. The present...

Construction of a replication-competent retroviral vector for expression of the VSV-G envelope glycoprotein for cancer gene therapy.

Mar 9, 2020

Gibbon ape leukemia virus (GALV) can infect a wide variety of cells but fails to infect most cells...

PIM protein kinases regulate the level of the long noncoding RNA H19 to control stem cell gene transcription and modulate tumor growth.

Mar 9, 2020

The PIM serine/threonine kinases have an oncogenic and pro-survival role in hematological and...

Leukocyte-related parameters in older adults with metabolic syndrome.

Mar 9, 2020

We aimed to examine the association between leukocyte-related parameters and the risk of metabolic...

Reliable blood cancer cells’ telomere length evaluation by qPCR.

Mar 9, 2020

Telomere shortening is linked to a range of different human diseases, hence reliable measurement...

The long-term oral exposure to titanium dioxide impaired immune functions and triggered cytotoxic and genotoxic impacts in rats.

Mar 9, 2020

Titanium dioxide “TiO, E171″ is a widely used food additive that exists in various everyday...

The effects of silver nanoparticles (Ag-NPs) sublethal concentrations on common carp (Cyprinus carpio): Bioaccumulation, hematology, serum biochemistry and immunology, antioxidant enzymes, and skin mucosal responses.

Mar 9, 2020

The present study aimed to evaluate the effects of different waterborne sublethal concentrations...

Investigation of the Status Quo of Veterinary Point-of-Care Laboratories in Switzerland: Availability, Application, and Quality Management.

Mar 9, 2020

The extent to which Swiss veterinary practitioners follow the guidelines for quality assurance of...

The role of deubiquitinating enzymes in cancer drug resistance.

Mar 9, 2020

Drug resistance is a well-known phenomenon leading to a reduction in the effectiveness of...

Antiproliferative evaluation of some 2-(2-Styrylcyclopent-3-enyl) benzo[d]thiazoles: DFT and molecular docking study.

Mar 9, 2020

The 2-(2-styrylcyclopent-3-enyl)benzo-[ d ]thiazoles (5a-m) were synthesized from the reaction of...

The Current Status of Immune Checkpoint Inhibitors in Neuro-Oncology: A Systematic Review.

Mar 9, 2020

The introduction of immune checkpoint inhibitors (ICI), as a novel treatment modality, has...

Quantifying the Financial Savings of Motion Correction in Brain MRI: A Model-Based Estimate of the Costs Arising From Patient Head Motion and Potential Savings From Implementation of Motion Correction.

Mar 9, 2020

Patient head motion is a major concern in clinical brain MRI, as it reduces the diagnostic image...

Predicting Confined 1D Cell Migration from Parameters Calibrated to a 2D Motor-Clutch Model.

Mar 9, 2020

Biological tissues contain micrometer-scale gaps and pores, including those found within...

Adult H3K27M-mutant diffuse midline glioma with gliomatosis cerebri growth pattern: Case report and review of the literature.

Mar 9, 2020

H3K27M-mutant diffuse midline glioma is a recently classified unique entity predominantly...

Follow Us

Month: March 2020