Low-density lipoprotein receptor-related protein 1 deficiency in cardiomyocytes reduces susceptibility to insulin resistance and obesity.

Mar 2, 2020

Low-density lipoprotein receptor-related protein 1 (LRP1) plays a key role in fatty acid...

Circulating and tissue specific transcription of angiopoietin-like protein 4 in human Type 2 diabetes.

Mar 2, 2020

Obesity is associated with adipose tissue (AT) dysfunction marked by cellular hypertrophy,...

Assessing Malnutrition before Major Oncologic Surgery: One Size Does Not Fit All.

Mar 2, 2020

There are multiple definitions for malnutrition, without evidence of superiority of any one...

PI3K inhibitor treatment ameliorates the glucocorticoid insensitivity of PBMCs in severe asthma.

Mar 2, 2020

Glucocorticoid (GC) insensitivity is an important feature of severe and fatal asthma. Oxidative...

Asthma Across Childhood: Improving Adherence to Asthma Management from Early Childhood to Adolescence.

Mar 2, 2020

Asthma affects nearly 6 million US children. Throughout childhood, children undergo a series of...

Prevalence and correlates of Attention Deficit Hyperactive Disorder (ADHD) risk factors among school children in a rural area of North India.

Mar 2, 2020

Attention-deficit hyperactive disorder (ADHD) is one of the most common neurodevelopmental...

Exposure to Environmental Toxicants and Early Language Development for Children Reared in Low-Income Households.

Mar 2, 2020

Considerable evidence has highlighted the heightened susceptibility of developmental delay in...

Educating Pediatric Residents About Parenting: A Survey of Residency Program Leaders.

Mar 2, 2020

The American Academic of Pediatrics guides pediatricians to counsel parents about how to promote...

Acute respiratory infection and its associated factors among children under-five years attending pediatrics ward at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: institution-based cross-sectional study.

Mar 2, 2020

Acute respiratory infection is manifested by cough accompanied by short rapid breathing which may...

EGFR signaling causes morphine tolerance and mechanical sensitization in rats.

Mar 2, 2020

The safety and efficacy of opioids are compromised as analgesic tolerance develops. Opioids are...

The endomorphin-1/2 and dynorphin-B peptides display biased agonism at the mu opioid receptor.

Mar 2, 2020

Opioid agonist activation at the mu opioid receptor (MOR) can lead to a wide variety of...

Morphine-3-glucuronide causes antinociceptive cross-tolerance to morphine and increases spinal substance P expression.

Mar 2, 2020

Morphine-3-glucuronide (M3G), the main metabolite of morphine, has been implicated in the...

Opioid prescriptions in emergency departments: Findings from the 2016 National Hospital Ambulatory Medical Care Survey.

Mar 2, 2020

In the past decade, there has been a rising trend in the emergency department (ED) visits in the...

Real-world assessment of concomitant opioid utilization and associated trends in patients with migraine.

Mar 2, 2020

Migraine is a debilitating condition that affects approximately 16% of adults and is the fifth leading cause of emergency department visits in the United States. There are several treatment options for migraines; opioids are...

Patient experience with non-invasive vagus nerve stimulator: gammaCore patient registry.

Mar 2, 2020

gammaCore is cleared by the FDA for acute and preventive treatment of cluster headache and the acute treatment of migraine in adults. Previously, only 2 treatments were approved for acute treatment of cluster headache while none...

Integrative East-West Medicine Intervention for Chronic Daily Headache: A Case Report and Care Perspective.

Mar 2, 2020

Chronic daily headache is a group of headache syndromes including most commonly chronic migraine...

To Eat or Not to Eat: A Review of the Relationship between Chocolate and Migraines.

Mar 2, 2020

Migraine is a chronic disorder with episodic attacks, and patients with a migraine often report that certain factors can trigger their headache, with chocolate being the most popular type of food-based trigger. Many studies have...