Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy.
Highly expressed in cancer 1 (Hec1) plays an essential role in mitosis and is correlated with...
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Month: March 2020
Preliminary Evidence of Pregabalin Misuse among Prescription and/or Illicit Opioid (Mis)users.
Pregabalin is approved for the management of neuropathic pain, partial-onset seizures, and...
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Rome IV Functional Gastrointestinal Disorders and Health Impairment in Subjects With Hypermobility Spectrum Disorders or Hypermobile Ehlers-Danlos Syndrome.
Individuals with hypermobility spectrum disorder or hypermobile Ehlers-Danlos Syndrome (HSD/hEDS)...
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Yoga therapy for fibromyalgia syndrome: A case report.
Fibromyalgia is a rheumatologic syndrome leading to increased pain sensitivity, sleep disturbance,...
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Pain catastrophizing mediates the negative influence of pain and trait-anxiety on health-related quality of life in fibromyalgia.
Patients with fibromyalgia syndrome (FMS) usually display a decrease in health-related quality of...
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New insights on the structure of alpha-synuclein fibrils using cryo-electron microscopy.
Fibrils of alpha-synuclein are significant components of cellular inclusions associated with...
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Priming older adults and people with mild to moderate Alzheimer’s disease problem-solving with false memories.
In two experiments we investigated whether older adult controls (OACs) and people with mild and...
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Diagnostic potential of automated tractography in progressive supranuclear palsy variants.
Microstructural white matter integrity captured by diffusion-tensor imaging (DTI) is significantly...
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Neocortical morphometry in Huntington’s disease: Indication of the coexistence of abnormal neurodevelopmental and neurodegenerative processes.
Huntington’s disease (HD) is an inherited, autosomal dominant disorder that is...
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Sleep Disorders in Children and Adolescents with Autism Spectrum Disorder: Diagnosis, Epidemiology, and Management.
Sleep problems are a common complaint in children/adolescents with autism spectrum disorder (ASD)....
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Does the Factor Structure of IQ Differ Between the Differential Ability Scales (DAS-II) Normative Sample and Autistic Children?
The Differential Abilities Scales, 2nd edition (DAS-II) is frequently used to assess intelligence...
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Longitudinal study of brain asymmetries in autism and developmental delays aged 2 to 5 years.
Some previous studies have demonstrated atypical brain lateralization in autism spectrum disorder...
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Autism: Implications for high secure psychiatric care and move towards best practice.
To explore the role of high secure psychiatric care (HSPC) in the assessment and management of...
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The Heart Failure with Preserved Ejection Fraction Conundrum-Redefining the Problem and Finding Common Ground?
Heart failure with preserved ejection fraction (HFpEF) or diastolic heart failure (DHF) makes up...
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Broader phenotypic traits and widespread brain hypometabolism in spinocerebellar ataxia 27.
The goal of this study was to characterize a Swedish family with members affected by...
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Associations between ADHD and emotional problems from childhood to young adulthood: a longitudinal genetically sensitive study.
Attention deficit/hyperactivity disorder (ADHD) is associated with emotional problems, and their...
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Long-lasting behavioral and neuroanatomical effects of postnatal valproic acid treatment.
Valproic acid (VPA) administered to mice during the early postnatal period causes social,...
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Pericallosal artery aneurysm – Case report, literature review and management outcome.
Pericallosal artery aneurysms are rare. Very few cases of this vascular anomaly have been...
Read MoreSternheimer-Malbin Staining to Detect Decoy Cells in Urine of 213 Kidney Transplant Patients.
Human polyoma virus-associated nephropathy frequently refers to allograft failure after kidney transplant. Thus, the early detection of viral activation is extremely important for these immunocompromised patients.Previously,...
Read MoreEvidence of Interleukin-2-Receptor-Antibody Induction in Low-Risk Living Donor Kidney Transplantation: A Single-Center Pilot Study.
The recommended standard immunosuppressive therapy for renal transplant recipients comprises an initial induction therapy mainly with an interleukin-2-receptor antibody (IL2-RA) and a triple maintenance therapy. With tacrolimus...
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