Ten chronic overlapping pain conditions are currently recognized by the National Institutes of Health Pain Consortium (e.g., irritable bowel syndrome, chronic migraine headache, and chronic low back pain). These conditions affect millions of Americans, however, assessing these conditions, their co-occurrence, and their relationship to treatment has proven challenging due to time-constraints and a lack of standardized measures. We present a Chronic Overlapping Pain Conditions Screener that is logic-driven, efficient, and freely available in electronic format to non-profit entities. Thirty experts were convened to identify and modify self-report criteria for each Chronic Overlapping Pain Condition as well as criteria that trigger the administration of the diagnostic criteria from a body map and brief series of questions. Their recommendations were then programmed into Research Electronic Data Capture platform and refined for comprehensibility and ease of use by patient focus groups. The electronic screener and physician-administered criteria were both administered to patients with known Chronic Overlapping Pain Conditions in a counter-balanced fashion to determine the level of agreement between methods. The expert panel identified screening items/body map regions and diagnostic criteria for all ten Chronic Overlapping Pain Conditions. Patients found the content comprehensible and the platform easy to use. Cohen’s Kappa statistics suggested good agreement between the electronic Chronic Overlapping Pain Condition -Screener and criteria administered by a physician (κ=.813). The Chronic Overlapping Pain Condition -Screener is an efficient tool for screening multiple Chronic Overlapping Pain Condition -Screener s and has applicability to research studies, clinical trials, and clinical practice. PERSPECTIVE: Assessing Chronic Overlapping Pain Conditions remains a challenge for researchers and clinicians. The Chronic Overlapping Pain Condition – Screener is an efficient and logic-driven electronic tool that allows for the rapid screening assessment of ten Chronic Overlapping Pain Conditions. The instrument may have utility in research and clinical settings.Copyright © 2023. Published by Elsevier Inc.