The following is a summary of “Incidence and predictors of deep incisional and organ/space surgical site infection following radical cystectomy,” published in the November 2023 issue of Urology by Blachman-Braun, et al.

For a study, researchers sought to look into the clinical risk factors connected with deep incisional or organ/space surgical site infections (SSI) after radical cystectomy (RC) in a big, well-known group of people who had the surgery recently. They looked through the American College of Surgeons National Surgical Quality Improvement Programme database to find 13,081 adults who had RC for bladder cancer between 2015 and 2020. In the 30 days after RC, they used multivariable-adjusted logistic regression and Cox-adjusted proportional hazards regression analysis to find clinical indicators of deep incisional or organ/space SSI.

If you had a continent urinary diversion (HR = 1.61, 95% CI = 1.38–1.88; P < 0.001), were overweight (HR = 1.60, 95% CI: 1.35–1.90; P < 0.001), diabetes (HR = 1.30, 95% CI: 1.13–1.51; P < 0.001), or were functionally dependent before surgery (HR = 2.09, 95% CI: 1.44–3.03; P < 0.001). 

Deep incisional or organ/space SSIs happen more often after RC in patients who were overweight, sick, or dependent on others before surgery, as well as in those who had continent urine diversion. The results could help urologists with preoperative counseling, medical optimization, and choosing the best method for urine diversion. They could also help with better patient tracking and finding people who might need help after surgery.

Source: sciencedirect.com/science/article/abs/pii/S1078143923002326