In patients with blood cancer, critical illness and baseline characteristics were associated with an increased risk of venous thromboembolism (VTE), according to research in Intensive Care Medicine. Federico C. Carini, MD, and colleagues conducted a populationbased cohort study of 76, 803 hospitalized adults with a new diagnosis of hematologic malignancy. VTE incidence was notably higher among ICU patients (3.7%) compared with non-ICU patients (1.2%), indicating a threefold increased risk (OR, 3.08; 95% CI, 2.77-3.42). Similarly, the occurrence of major bleeding was 7.6% in ICU patients versus 2.4% in non-ICU patients (OR, 3.33; 95% CI, 3.09-3.58). Even after adjusting for potential confounders, the association between critical illness and VTE remained significant (OR, 2.92; 95% CI, 2.62-3.25). Specific subtypes of hematologic malignancy and prior history of VTE were linked with higher VTE incidence, while delayed admission post-diagnosis and lower platelet count at hospitalization were associated with reduced VTE risk.