Researchers recently explored the relationship between sarcopenia and phase angle in patients with hematologic malignancies undergoing chemotherapy and exercise therapy. The study, published in Nutrition and Cancer, included 108 patients who participated in assessments of muscle strength, endurance, and body composition, including phase angle. The researchers conducted logistic regression and ROC analyses to investigate associations and determine phase angle cutoff values. Sarcopenia was present in 17.6% of the participants. Phase angle was significantly associated with sarcopenia (P<0.01), with AUC values of 0.84 for men and 0.87 for women. The phase angle cutoff values were 4.75° for men (sensitivity 69%, specificity 83%) and 3.95° for women (sensitivity 78%, specificity 85%). The researchers reported that phase angle, which can be measured noninvasively, quickly, and objectively, can serve as an effective screening tool for sarcopenia in patients with hematologic malignancies.
