The following is a summary of “Clinical outcomes and optical performance of a new segmental refractive extended depth-of-focus intraocular lens,” published in the August 2024 issue of Ophthalmology by Amaro et al.

Researchers conducted a retrospective study evaluating the visual performance and optical quality of a segmental refractive extended-depth-of-focus (EDoF) intraocular lens (IOL).

They included 20 patients (40 eyes) who underwent bilateral refractive segmental EDoF Acunex Vario AN6V implantation. The assessments included refraction outcomes, monocular and binocular uncorrected visual acuity (UCVA) and distance-corrected visual acuity (DCVA), defocus curve, contrast sensitivity (CS), higher-order aberrations (HOAs), and patient satisfaction, and the evaluations were conducted at 1 and 3 months post-surgery.

The result showed the mean spherical equivalent was −0.23 ± 0.32 D at the 3-month follow-up. Binocular UCVA was −0.08 ± 0.06 logMAR at 4 meters (distance), −0.03 ± 0.06 logMAR at 66 cm (intermediate), and 0.16 ± 0.06 logMAR at 40 cm (near). The binocular defocus curve indicated a VA better than 0.20 logMAR over a range of +1.50 to −2.45 D. The CS was comparable to monofocal lenses, underscoring the clinical value of the lens. Aberrometry indicated minimal changes in corneal aberrations. The NEI-RQL-42 Questionnaire revealed high patient satisfaction with daily activities and reduced dependence on glasses, especially for near and intermediate vision. The Acunex Vario AN6V exhibited minimal dysphotopsias, positioning it as a promising option for patients seeking reduced spectacle dependence.

Investigators concluded that the segmental refractive EDoF IOL offered significant spectacle independence for far and intermediate distances, with functional near VA and minimal dysphotopsias despite inducing some residual coma aberrations.

Source: bmcophthalmol.biomedcentral.com/articles/10.1186/s12886-024-03586-4