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The following is a summary of “Effect of different maneuvers of repositioning on benign paroxysmal vertigo: a network meta-analysis,” published in the March 2025 issue of BMC Neurology by Si et al. 

Researchers conducted a prospective study using network meta-analysis to evaluate the effect of different repositioning maneuvers on benign paroxysmal vertigo.  

They searched PubMed, Embase, Cochrane Library, and Web of Science for randomized controlled studies on manipulative repositioning for benign paroxysmal vertigo until September 1, 2024. Data were analyzed using Bayesian network meta-analysis in R4.4.1. Adults meeting Benign Paroxysmal Positional Vertigo (BPPV) diagnostic criteria were included, and remission rates were assessed. Interventions included Epley maneuver (EM); Usual treatment (UT) containing conventional medications; Semont’s maneuver (SM); Brandt-Daroff (BD); Gans Repositioning Maneuvers (GRM); repeated Dix-Hallpike test (rDHt); Barbecue rotation maneuver (BRM); Gufoni maneuver (GFM); Self- Epley (SEM). 

The results showed that 22 studies (n = 2,507) were included. Network meta-analysis found the following odds ratios (OR) vs control group UT: EM (7.9, 95% CI: 3.21–23.31), GFM (5.1, 95% CI: 1.25–21.45), GRM (11, 95% CI: 1.65–83.85), Modified Epley maneuver (MEM) (9.83, 95% CI: 1.55–64.06), and SM (6.1, 95% CI: 1.97–18.46). The highest SUCRA was GRM (71.5%), followed by MEM (68%) and SEM (67.8%), with UT lowest (5.7%). 

Investigators found GRM, MEM, and SEM effective for BBPV symptoms but noted study limitations. More high-quality, multicenter, large sample randomized controlled studies were needed to confirm the findings. 

Source: bmcneurol.biomedcentral.com/articles/10.1186/s12883-025-04123-6