Serum zinc levels in patients with hidradenitis suppurativa (HS) had never been investigated. For a study, researchers wanted to determine to look at the link between HS and serum zinc levels. A multicenter, prospective clinical and analytical case-control research was planned to investigate the putative link between HS and serum zinc levels. Patients with moderate to severe HS (Hurley II or III only) were included in a series of studies. Primary care clinics were used to recruit a control population. Each patient’s serum zinc levels were evaluated after fasting blood samples were taken. Using logistic regression models, potential predictors of low blood zinc levels were determined.
In all, 122 patients with HS and 122 healthy controls were investigated. There were 79 (64.8%) Hurley II patients and 43 (35.2%) Hurley III patients among the 122 HS patients. Low blood zinc levels (83.3 g/dL) were shown to be more common in HS (adjusted odds ratio [ORa] 6.7, P<0.001). Low serum zinc levels were linked with Hurley III (ORa 4.4, P=0.001), Dermatology Life Quality Index 9 (ORa 3.1, P=0.005), a number of afflicted sites 3 (ORa 2.4, P=0.042), genital location (ORa 2.9, P=0.009), and perineal location (ORa 2.5, P=0.025) after logistic regression analysis.
Low blood zinc levels were more common in HS patients than in the general population, and this signal might be related to illness severity.
Reference:link.springer.com/article/10.1007/s40257-018-0374-5
