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AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathway.

Feb 12, 2024

ABOUT THE EXPERTS

  • Yizhi Zhang

    The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.

    Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.

    Wan Li

    The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.

    Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.

    Yihui Yang

    The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.

    Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.

    Sen Zhang

    The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.

    Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.

    Hong Yang

    The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.

    Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.

    Yue Hao

    The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.

    Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.

    Xu Fang

    The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.

    Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.

    Guanhua Du

    The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China.

    Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China.

    Jianyou Shi

    Department of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, Sichuan, China. shijianyoude@126.com.

    Lianqiu Wu

    Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. wlq@imm.ac.cn.

    Jinhua Wang

    The State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing, 100050, China. wjh@imm.ac.cn.

    Key Laboratory of Drug Target Research and Drug Screen, Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100050, China. wjh@imm.ac.cn.

REFERENCES & ADDITIONAL READING

PubMed

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