The following is a summary of “Mitochondrial control of antigen presentation in cancer cells,” published in the November 2023 issue of Oncology by Soler-Agesta et al.
If cytotoxic T lymphocytes come into touch with cancer cells, they can identify and kill those cancer cells without taking any more action. Complex antigenic epitopes with MHC class I molecules are found on the surface of cancer cells. This specific phenomenon takes place as a result of this particular cause. This is the reason why things transpire in the manner that they do.
For a study, researchers sought to demonstrate that the changes in the electron transport within the mitochondria had been found to upregulate many components involved in antigen presentation through a succinate-dependent epigenetic process. This was demonstrated by the fact that the enzymes involved in the antigen presentation were upregulated.
It was proved that the mitochondria were discovered to display the alterations in electron transport exhibited by the mitochondria. Their ability to present proof that these adjustments were discovered is evidence that this specific point was proven. It was evidence that the particular point was proven. It was shown that this is the case via examining the immunological response, which served as the basis for the investigation.
Source: sciencedirect.com/science/article/abs/pii/S1535610823003574
