The following is a summary of “Evaluation of the height of the corpus callosum body region in fetal meningomyelocele malformation,” published in the September 2023 issue of Gynecology Obstetrics and Human Reproduction by Akbas et al.
This study aims to measure the height of the corpus callosum (CC) so that abnormalities in the CC of fetuses with meningomyelocele (MMC) can be described and compared to the CC of healthy fetuses. In this investigation, fetal MRI was performed on 44 cases of fetal MMC malformation. As the control group, 34 anatomically normal fetal MRI examinations were evaluated retrospectively. In the study group, the lateral ventricle’s diameter, the MMC defect’s level and diameter, and the CC’s height were evaluated.
The CC height and lateral ventricular diameter were measured in the control group. The average CC body height in the experimental group was 1.36 mm, while it was 2.48 mm in the control group. The height of the CC body region of the population under study tended to be smaller than that of the control population (P<0.001).
The finding that the height of the CC body region was smaller in MMC fetuses compared to normal fetuses suggests that various callosal anomalies are uncertain and that investigating additional callosal anomalies may be beneficial in determining whether to continue the pregnancy, terminate the pregnancy, or perform intrauterine surgery in MMC cases. Additional large-scale case-group investigations are required.
Source: sciencedirect.com/science/article/abs/pii/S2468784723000867
