CME/CE: A Clinician’s Guide to Surrogate Endpoints in Hematology
This course discusses a study that intends to change the statistician and clinician process by...
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CME/CE: Medical, Psychiatric Comorbidities Common in New-Onset & Incident Epilepsy
This course discusses a study that was looking to find which chronic conditions may be risk...
Read MoreThe efficacy analysis of robotic versus laparoscopic ipsilateral uretero-ureterostomy for upper urinary tract duplications in pediatric population.
To review and compare robot-assisted ipsilateral ureteroureterostomy (RALUU) and laparoscopic ipsilateral uretero-ureterostomy (LUU) in terms of efficacy and outcomes.Clinical data of 65 children with complete renal ureteral...
Read MoreHematopoietic stem cell transplantation in inborn errors of metabolism-a retrospective analysis on behalf of the pediatric disease working party from the Brazilian Society of Bone Marrow Transplantation and Cellular Therapy.
Hematopoietic stem cell transplantation (HSCT) is an established treatment for selected patients with inborn errors of metabolism. In this first report from the PDWP-SBTMO, we included 105 patients transplanted between 1988 and...
Read MoreA preliminary ex vivo diffusion tensor imaging study of distinct aortic morphologies.
Changes in the microstructure of the aortic wall precede the progression of various aortic pathologies, including aneurysms and dissection. Current clinical decisions with regards to surgical planning and/or radiological...
Read MoreAltered medial temporal lobe subregion volumes in systemic lupus erythematosus patients with neuropsychiatric symptoms.
Systemic lupus erythematosus (SLE) often presents with neuropsychiatric (NP) involvement, including cognitive impairment and depression. Past magnetic resonance imaging (MRI) research in SLE patients showed smaller hippocampal...
Read MoreAssociation of dietary acid load with inflammatory markers, oxidative stress, and clinical features in patients with knee osteoarthritis.
Knee osteoarthritis (KOA) is a prevalent chronic condition characterized by inflammation and oxidative stress, particularly in individuals over 40. Dietary factors, specifically dietary acid load (DAL), may influence these...
Read MoreDistinct relative abundances in pathogens detected in mechanically ventilated patients with suspected pneumonia in the intensive care unit at King Abdulaziz University Hospital.
In this study, we present for the first time the landscape of the lung microbiota in patients with ventilator-associated pneumonia in Intensive Care Units in Saudi Arabia. DNA from 83 deep endotracheal aspirate lung samples was...
Read MoreLipopolysaccharide Causes Acquired CFTR Dysfunction in Murine Nasal Airways.
Cystic fibrosis (CF) is a clinical entity defined by aberrant chloride (Cl) ion transport causing downstream effects on mucociliary clearance (MCC) in sinonasal epithelia. Inducible deficiencies in transepithelial Cl transport...
Read MoreExploring the effects of aromatherapy and acupoint herbal patching on fatigue and sleep disorders in people living with HIV: a pilot randomized trial.
The purpose of this study was to investigate the effects of aromatherapy and acupoint herbal patching on fatigue and sleep disorders in people living with HIV (PLWH). Aromatherapy and acupoint herbal patching are ancient...
Read MoreThe Association Between Hearing Loss and Depression in a Large Electronic Health Record System.
Hearing loss (HL) is associated with depression, but existing datasets are limited by the type of data available for both hearing and mental health conditions. The purpose of this study is to determine if there is an association...
Read MoreA Qualitative Analysis of Immigrant Latinx Housecleaners’ Experiences of How Power Relations With “Employers” Influence Working Conditions in New York City: The Safe and Just Cleaners Study.
Housecleaning work has been characterized as precarious employment with unstable work hours, arbitrary and low pay and benefits, and exposures to chemical, physical, and psychosocial stressors. Understanding how interpersonal...
Read MoreThe difference of oropharyngeal microbiome during acute respiratory viral infections in infants and children.
Acute respiratory infections (ARI) with multiple types of viruses are common in infants and children. This study was conducted to assess the difference of oropharyngeal microbiome during acute respiratory viral infection using...
Read MoreDevelopment and implementation of a Sezer gastrostomy care bundle using the Knowledge to Action framework.
This project aimed to develop an evidence-based nursing care bundle after gastrostomy feeding tube insertion and implement it into clinical practice using the Knowledge to Action (KTA) framework.This mixed-method design project...
Read MoreLifetime Body Mass Index Trajectories and Contrasting Lung Function Abnormalities in Mid-Adulthood: Data From the Tasmanian Longitudinal Health Study.
The impact of lifetime body mass index (BMI) trajectories on adult lung function abnormalities has not been investigated previously. We investigated associations of BMI trajectories from childhood to mid-adulthood with lung...
Read MoreA comprehensive analysis of trends in the burden of gout in China and globally from 1990 to 2021.
Gout is a prevalent metabolic disorder characterized by urate crystal accumulation in joints, leading to acute arthritis and tophi formation. Despite advancements in management, the incidence and prevalence of gout have been...
Read MoreComputerized Tomography for Diagnosing Traumatic Arthrotomies of the Ankle.
Owing to the risk for septic arthritis, traumatic arthrotomies are an urgent surgical problem for the treating orthopaedic surgeon. Traditionally, diagnosis is with the saline load test (SLT), although in the awake patient is an...
Read MoreInfluence of HLA-B Leader (-21M/T) Dimorphism With Bw4/Bw6 Epitopes on Graft Versus Host Disease After Allogenic Haematopoietic Stem Cell Transplantation in North Indians.
High degree of variability in human leukocyte antigens (HLAs) system restricts availability of histocompatible HLA-matched-related donors, thus increasing reliance on worldwide bone marrow registries network. Nevertheless, due...
Read MoreEvaluation of dry eye parameters and meibomian gland function using the Lipiscan system in male androgenetic alopecia patients.
The prevalence of male androgenetic alopecia is increasing worldwide. Evaluation of dry eye parameters and meibomian glands of male androgenetic alopecia patients may help to better understand the effect of this disease on dry...
Read MoreStatistical identification of cell type-specific spatially variable genes in spatial transcriptomics.
An essential task in spatial transcriptomics is identifying spatially variable genes (SVGs). Here, we present Celina, a statistical method for systematically detecting cell type-specific SVGs (ct-SVGs)-a subset of SVGs...
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