Overexpression of YES1 is associated with favorable prognosis and increased platinum-sensitivity in patients with epithelial ovarian cancer.
The prognostic application of YES1 in epithelial ovarian cancer (EOC) is currently unclear. We...
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Mutually exclusive antiproliferative effect of cell line-specific HOX inhibition in epithelial ovarian cancer cell lines: SKOV-3 vs RMUG-S.
We aimed to discover cell line-specific overexpressed HOX genes responsible for chemoresistance...
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Tuning Nanoparticle Interactions with Ovarian Cancer through Layer by Layer Modification of Surface Chemistry.
Nanoparticle surface chemistry is a fundamental engineering parameter that governs tumor-targeting...
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Synthesis, mechanisms of action, and toxicity of novel aminophosphonates derivatives conjugated irinotecan in vitro and in vivo as potent antitumor agents.
Twenty novel aminophosphonates derivatives (5a-5j and 6a-6j) conjugated irinotecan were...
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Antitumor activity of triptolide in SKOV3 cells and SKOV3/DDP in vivo and in vitro.
This study was designed to investigate the antitumor activity of triptolide in ovarian cancer...
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Correlation between cytogenetic abnormalities and disease characteristics in multiple myeloma: monosomy of chromosome 13 and structural abnormalities of 11q are associated with a high percentage of S-phase plasma cells.
Cytogenetic studies in multiple myleoma (MM) are limited by the difficulties in obtaining...
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Randomized Phase II trial of thalidomide alone versus thalidomide plus interferon alpha in patients with refractory multiple myeloma.
The potential synergistic anti-myeloma effect for thalidomide combining with interferon alpha was...
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Bias analysis applied to Agricultural Health Study publications to estimate non-random sources of uncertainty.
The associations of pesticide exposure with disease outcomes are estimated without the benefit of...
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Role of NKG2D in cytokine-induced killer cells against multiple myeloma cells.
The cytokine-induced killer cells (CIK) have been reported to have potent cytotoxicity against a...
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Tetraspanin 7 (TSPAN7) expression is upregulated in multiple myeloma patients and inhibits myeloma tumour development in vivo.
Increased expression of the tetraspanin TSPAN7 has been observed in a number of cancers; however,...
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Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-Apoptotic Mcl-1 and Bfl-1 Proteins.
Anti-apoptotic Bcl-2 family proteins are overexpressed in a wide spectrum of cancers and have...
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ROLE OF DIAGNOSTIC PARS PLANA VITRECTOMY IN DETERMINING THE ETIOLOGY OF UVEITIS INITIALLY UNKNOWN.
To estimate the success and safety of diagnostic pars plana vitrectomy (PPV) in determining the...
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The emerging role of dipeptidyl-peptidase-4 as a therapeutic target in lung disease.
: Dipeptidyl-peptidase-4 (DPP-4) is a surface bound ectopeptidase that is commonly known as CD26...
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Human papillomavirus infection maybe not associated with primary lung cancer in the Fujian population of China.
To investigate whether human papillomavirus (HPV) infection is associated with primary lung cancer...
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Chemoradiation and granulocyte-or granulocyte macrophage-colony stimulating factors (G-CSF or GM-CSF): Time to think out of the box?
Concerns have been raised about potential toxic interactions when colony-stimulating factors...
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Clinical consequences of resistance to inhibitors in non-small cell lung cancer.
: rearrangements are present in 2-7% of non-small cell lung cancer (NSCLC) cases, where the fusion...
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Osimertinib overcomes alectinib resistance caused by amphiregulin in a leptomeningeal carcinomatosis model of ALK-rearranged lung cancer.
Leptomeningeal carcinomatosis (LMC) occurs frequently in anaplastic lymphoma kinase...
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Feed-forward Regulatory Loop Driven by IRF4 and NF-κB in Adult T-cell Leukemia/Lymphoma.
Adult T-cell leukemia/lymphoma (ATL) is a highly aggressive hematological malignancy derived from...
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Overexpression of ABCG2 confers resistance to pevonedistat, an NAE inhibitor.
Pevonedistat is a potent, selective, first-in-class NEDD8 activating enzyme inhibitor. It is now...
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HISTOLOGIC FINDINGS IN VITREORETINAL LYMPHOMA: Learning From Enucleation Specimens.
We aimed to describe the clinical and histologic findings in a few enucleation cases with...
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