Genetic variability of T cell responses in Hypersensitivity Pneumonitis identified using the BXD genetic reference panel.
Hypersensitivity pneumonitis is an interstitial lung disease that may progress to fibrosis and...
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Allergic inflammation is initiated by IL-33-dependent crosstalk between mast cells and basophils.
IgE-primed mast cells in peripheral tissues, including the skin, lung, and intestine, are key...
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Food aversion and poor weight gain in food protein-induced enterocolitis syndrome: a retrospective study.
Food protein-induced enterocolitis syndrome (FPIES) is a form of non-IgE mediated gastrointestinal...
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Prevalence and impact of comorbid laryngeal dysfunction in asthma: A systematic review and meta-analysis.
Laryngeal or vocal cord dysfunction has long been regarded as a mimic of asthma; however recent...
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Niemann-Pick C1 Heterogeneity of Bat Cells Controls Filovirus Tropism.
Fruit bats are suspected to be natural hosts of filoviruses, including Ebola virus (EBOV) and...
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Preventing acute kidney injury and improving outcome in critically ill patients utilizing risk prediction score (PRAIOC-RISKS) study. A prospective controlled trial of AKI prevention.
Acute kidney injury (AKI) has significant impact on mortality and morbidity in critically ill...
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Plant-based diets for prevention and management of chronic kidney disease.
Plant-based diets have been used with growing popularity for the treatment of a wide range of...
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Exploring Care Attributes of Nephrologists Ranking Favorably on Measures of Value.
Despite growth in value-based payment, attributes of nephrology care associated with payer-defined...
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Using Electronic Health Record Data to Rapidly Identify Children with Glomerular Disease for Clinical Research.
The rarity of pediatric glomerular disease makes it difficult to identify sufficient numbers of...
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A Randomized Trial Comparing the Safety, Adherence, and Pharmacodynamics Profiles of Two Doses of Sodium Bicarbonate in CKD: the BASE Pilot Trial.
Oral sodium bicarbonate (NaHCO) may preserve kidney function in CKD, even if initiated when serum...
Read MoreUltrasound-Mediated Long-Circulating Nanopolymer Delivery of Therapeutic siRNA and Antisense MicroRNAs Leads to Enhanced Paclitaxel Sensitivity in Epithelial Ovarian Cancer Chemotherapy.
Epithelial ovarian cancer (EOC) is one of the leading malignant tumors that seriously threaten women’s health. The development of new drugs or increasing the sensitivities of current chemotherapy drugs is critically...
Read MoreA fluorescent probe for specific detection of β-galactosidase in living cells and tissues based on ESIPT mechanism.
β-galactosidase is of great significance to living organisms, which is an important marker of primary ovarian cancer and cellular senescence. To detect the activity of β-galactosidase, a novel fluorescent probe ESIPT-GAL which...
Read MoreBias analysis applied to Agricultural Health Study publications to estimate non-random sources of uncertainty.
The associations of pesticide exposure with disease outcomes are estimated without the benefit of a randomized design. For this reason and others, these studies are susceptible to systematic errors. I analyzed studies of the...
Read MoreFollicular B-Cell Lymphoma and Particulate Matter Associated with Environmental Exposure to Wood Dust.
BACKGROUND In humans, wood dust is a carcinogen. Indeed, a strong association between wood dust and lung cancer risk has been reported in woodworkers, as well as in the general population. CASE REPORT The patient was a...
Read MoreIncidence and treatment of feline renal lymphoma: 27 cases.
Lymphoma is the most common feline hematopoietic malignancy. Incidence of renal lymphoma has not been reported as a subset of a large population of feline lymphoma cases. Previous studies have reported renal lymphoma as both a...
Read MoreReversal of Resistance to Anti-CD20 Antibody Therapies: Targeting Intracellular Resistant Factors.
Rituximab, a chimeric mouse/human monoclonal antibody (mAb) targeting CD20, has proven to improve treatment outcomes in a number of B-cell malignancies, including chronic lymphocytic leukemia (CLL), diffuse large B-cell lymphoma...
Read MoreTetraspanin 7 (TSPAN7) expression is upregulated in multiple myeloma patients and inhibits myeloma tumour development in vivo.
Increased expression of the tetraspanin TSPAN7 has been observed in a number of cancers; however, it is unclear how TSPAN7 plays a role in cancer progression.We investigated the expression of TSPAN7 in the haematological...
Read MoreRole of NKG2D in cytokine-induced killer cells against multiple myeloma cells.
The cytokine-induced killer cells (CIK) have been reported to have potent cytotoxicity against a variety of tumor cells including multiple myleoma (MM) cells. The mechanisms that CIK cell recognizing MM cells remain unknown....
Read MoreRNA splicing and aggregate gene expression differences in lung squamous cell carcinoma between patients of West African and European ancestry.
Despite disparities in lung cancer incidence and mortality, the molecular landscape of lung cancer in patients of African ancestry remains underexplored, and race-related differences in RNA splicing remain unexplored.We...
Read MoreDown-regulation of MALAT1 aggravates polycystic ovary syndrome by regulating MiR-302d-3p-mediated leukemia inhibitory factor activity.
Accumulating evidence have shown the important roles of long noncoding RNA (lncRNA) in controlling different diseases. In the present study, we tried to explore the role which lncRNA MALAT1 plays in polycystic ovary syndrome...
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