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In April 2017, the Central Denmark Region Antibiotic Stewardship Committee issued a directive to reduce the general use of piperacillin-tazobactam and to prescribe narrow spectrum antibiotics for mild and moderate pneumonia. The...

Cases of maternal near miss are those in which women survive severe maternal complications during pregnancy or the puerperium. This ecological study aimed to identify the temporal trend of near-miss cases in different regions of...

Sepsis, caused by the inappropriate host response to infection, is characterized by excessive inflammation response and organ dysfunction, continues to be a critical clinical problem. Commonly, sepsis may progress to septic...

We reported four cases of intramural haematoma of the descending thoracic aorta. Four patients, aged 55-82 years, hypertensive, were transferred from the emergency room of other hospitals due to the appearance of epigastric pain...

Despite the latest advances in cardiovascular biology and medicine, myocardial infarction (MI) remains one of the major causes of deaths worldwide. While reperfusion of the myocardium is critical to limit the ischemic damage...

A limitation of the Agatston coronary artery calcium (CAC) score is that it does not use all of the calcium density information in the computed tomography scan such that many individuals have a score of zero. We examined the...

After adequate fluid resuscitation in the early stage of septic shock, excessive accumulation of fluid in the body leads to organ dysfunction, which prolongs hospitalization, mechanical ventilation time, and renal replacement...

The Geriatrics Unit in University of Benin Teaching Hospital (UBTH), Nigeria was established in March 2014 to provide specialized healthcare to older persons. We undertook a review of admissions into the unit in order to...

Sepsis, caused by the inappropriate host response to infection, is characterized by excessive inflammation response and organ dysfunction, continues to be a critical clinical problem. Commonly, sepsis may progress to septic...

Tuberculosis (TB) rates among Tibetan refugee children and adolescents attending boarding schools in India are extremely high. We undertook a comprehensive case finding and TB preventive treatment (TPT) program in 7 schools in...

Brain-derived neurotrophic factor (BDNF) plays an important role in processes associated with neuroplasticity and neuroprotection. Evidence suggests that decreased BDNF levels in the central nervous system (CNS) represent a...

Computational human body models (HBM) present a novel approach to predict brain response in football impact scenarios, with prescribed kinematic boundary conditions for the HBM skull typically used at present. However,...

Sudden cardiac death (SCD) is the main preventable cause of death in adult congenital heart disease (ACHD) patients. Since robust risk stratification methods are lacking, we developed a risk score to predict SCD in ACHD...

To identify risk-factors for 30-day hospital readmission in systemic sclerosis pulmonary hypertension (SSc-PH) and to compare trends and characteristics of 30-day readmissions in SSc-PH versus non-SSc pulmonary arterial...

Using a nationwide epidemiological database, we aimed to clarify the association of fasting plasma glucose (FPG) with subsequent cardiovascular disease (CVD) risk among young adults.Medical records of 1,180,062 young adults...

Right ventricular (RV) failure is a common complication in moderate-to-severe acute respiratory distress syndrome (ARDS). RV failure is exacerbated by hypercapnic acidosis and overdistension induced by mechanical ventilation....

During the COVID-19 pandemic, creating tools to assess disease severity is one of the most important aspects of reducing the burden on emergency departments. Lung ultrasound has a high accuracy for the diagnosis of pulmonary...

In Japan, public dialog on allocation of life-saving medical resources remains taboo, and discussion has largely been avoided.Do Japanese health care workers and the general public agree with principles of ventilator allocation...

BACKGROUND Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily affects the lungs but can involve any organ. The medical community is struggling to cope with the...

This study comprehensively estimated the excess cardiovascular disease (CVD) mortality attributable to influenza in an older (age ≥65 years) population.Ecological study.Aggregated data from administrative systems on CVD...