Transient Anti-TCRβ mAb Treatment Induces CD4 T Cell Exhaustion and Prolongs Survival in a Mouse Model of Systemic Lupus Erythematosus.
T cells play a critical role in the pathogenesis of systemic lupus erythematosus (SLE). Chronic T cell receptor (TCR) signalling induces T cell exhaustion, characterised by reduced capacity to induce tissue damage. Here, we...
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