Nivolumab obtained approval in advanced melanoma (AM) with weight-adjusted dose (WAD) administration (3 mg/kg/2 weeks). In 2018, the dosage regimen was changed to flat dose (FD) administration (240 mg/2 weeks or 480 mg/4 weeks)...
Read MoreCeliac artery stenosis presents significant risks in pancreatoduodenectomy (PD), including elevated incidences of postoperative hepatic ischemia and clinically relevant pancreatic fistulae. Addressing this stenosis...
Read MoreElectric biking (e-biking) is a rapidly growing recreation, sport, and mode of transportation that often presents to emergency departments (EDs) with high-impact head injuries. This study aimed to evaluate the epidemiology of...
Read MoreCarfilzomib (CFZ), a second-generation proteasome inhibitor, is a key treatment for multiple myeloma (MM), but its use is associated with significant cardiovascular adverse events (CVAEs), including heart failure and...
Read MoreWe explore the association between hypoglycaemia fear (FH) and glycaemia during and after exercise sessions in a large sample of physically active youth with type 1 diabetes (T1D).We used data from the Type 1 Diabetes Exercise...
Read MoreEctopic fat is reduced by effective weight management, but difficult to assess clinically.We evaluated paired data on 42 participants in the intervention group of the Diabetes Remission Clinical Trial (DiRECT) at baseline, 12...
Read MoreThe PCSK9 protein binds to LDL receptors (LDLR), leading to their degradation and reduced expression on cell surfaces. This decreased the clearance of LDL cholesterol from the bloodstream, thereby increasing the risk of coronary...
Read MoreRecent studies suggest the existence of an idiopathic pulmonary arterial hypertension (IPAH) phenotype affecting mostly patients with a smoking history, characterised by low diffusion capacity for carbon monoxide (D) without...
Read MoreThis study investigates the association between climate and childhood asthma in Australia. Data from the Longitudinal Study of Australian Children (LSAC) was used to analyse this association in children who were 6-15 years...
Read MoreInterleukin-2 (IL-2) is a well-known cytokine that plays a crucial role in stimulating immune cells, including natural killer (NK) cells and cytotoxic T cells. It has been studied as an immunotherapy for a variety of diseases,...
Read MoreSoft tissue filler injection is the second most commonly performed cosmetic procedure worldwide, with augmentation rhinoplasty being the most common filling surgery in Asian countries because Asians predominantly have a low...
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1. In a cohort of patients with hyperglycemia, adherence to a Mediterranean diet (MED) was...
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1. In this randomized trial, amivantamab-lazertinib led to significantly longer progression-free...
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1. C-reactive protein (CRP)-point-of-care tests can be used to guide antibiotic prescribing in...
Read MoreFederal law requires that all nonprofit hospitals have financial assistance policies — also known as “charity care” — to reduce or expunge people’s medical bills. New research from Dollar For, an organization...
Read MoreIn 2017, the Republicans who controlled Congress tried mightily to slash federal spending on Medicaid, the government-funded health program covering low-income families and individuals. California, like other states, depends...
Read MoreThe Host Julie Rovner KFF Health News @jrovner Read Julie’s stories. Julie Rovner is chief Washington correspondent and host of KFF Health News’ weekly health policy news podcast, “What the Health?” A...
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1. The use of rituximab, abatacept and Janus kinase inhibitors (JAKis) in individuals with...
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1. Cadonilimab plus chemotherapy significantly improved progression-free survival in patients with...
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The ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol is...
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