In patients with epilepsy taking antiseizure and psychotropic medications, drug-drug interactions may not substantially impact outcomes as expected.
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Former smokers, especially those with COPD, have thinner airway walls, a measure that may help predict and manage COPD disease progression.
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Determinants of obesity and diabetes are strongly linked to genetic and epigenetic variations....
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Tezepelumab therapy cessation leads to a gradual increase in biomarkers and clinical outcomes, suggesting a potential disease-modifying effect.
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Prenatal exposure to air pollutants can trigger autophagy and senescence in newborns; autophagy-related biomarkers vary with air pollution levels.
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Factors influencing fatigue in patients with COPD include shortness of breath, higher pain levels, poor sleep quality, and fatigue-catastrophizing.
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Combining idrevloride and hypertonic saline in treatment of primary ciliary dyskinesia improves lung function and QOL without risk for hyperkalemia.
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82% of patients with chronic thromboembolic pulmonary hypertension undergo pulmonary...
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Efzofitimod, a biologic immunomodulator, reduces steroid dependency and improves lung function in pulmonary sarcoidosis, offering hope for a novel treatment.
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Gefapixant, a P2X3 receptor antagonist, improved chronic cough severity and QOL, but 13% of patients discontinued due to taste-related side effects.
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Long-term CPAP use in patients with obstructive sleep apnea linked to lower cardiovascular death risk and improved outcomes in real-world study.
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Extended sotatercept as an add-on treatment for pulmonary arterial hypertension maintained long-term benefit, with low treatment-related discontinuation.
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Myeloid inflammation and complement activation are linked to long COVID symptoms; distinct profiles observed in cognitive impairment and GI symptoms.
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An investigational drug, BMS-986278, reduced ppFVC decline in progressive pulmonary fibrosis, regardless of background therapy.
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Among patients with severe asthma, the need for biologic therapy varies by clinical stage. Mepolizumab is the preferred choice.
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Coronary artery calcification can effectively stratify risk for all-cause and cardiovascular (CV) mortality in people with obesity with no prior CV disease.
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Early-life exposures affect pediatric respiratory health, but healthy lifestyle behaviors during pregnancy can mitigate these risks.
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Maturing infant gut microbiota is associated with lower childhood risk for allergy-related wheezing and asthma.
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Patients with severe eosinophilic asthma taking benralizumab may reduce high-dose inhaled corticosteroids/formoterol while maintaining symptom control.
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Gabapentinoid use in patients with COPD increases the risk for severe exacerbation by almost 50%, underscoring the need for coordinated care.
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