LOXL2 a Therapeutic Target for Primary Myelofi brosis
Findings from a recent study suggest LOXL2 plays a critical role in the pathogenesis of primary myelofibrosis.
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Author: Teresa Sellinger
Low-Risk Myelofibrosis Shows Evidence of Disease Progression
About 60% of patients with low-risk myelofibrosis showed evidence of disease progression during 4 years of follow-up.
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Report Describes Rare Co-Occurrence of JAK2, CALR & MPL Mutations
The novel co-occurrence of JAK2, CALR & MPL mutations in a patient with myelofibrosis challenges previous knowledge that driver mutations cannot coexist.
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How Tumor Stiffness Adds Value to Endometrial Cancer Assessment
Combining MR elastography with clinical radiological data improved the prediction of lymphovascular space invasion in patients with endometrial cancer.
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Q&A: A New Approach to Improve Liver Transplant Rates in Septuagenarians
Liver transplants from older donors can be effective for septuagenarian candidates and are associated with lower mortality and shorter time to transplant.
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Shear Wave Elastography Distinguishes Myelofibrosis From Other MPNs
Spleen and liver elastography can help diagnose myeloproliferative neoplasms and differentiate myelofibrosis from other myeloproliferative neoplasms.
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Usher Syndrome Type IV Genetic Landscape Expanded More Than 30%
Researchers have increased the number of patients with ARSG-Usher syndrome type IV to 31 cases and...
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Q&A: Key Aspects of Memory in MS Improved With Cognitive Rehab
Dr. Elizabeth Gromisch discusses her study, which showed the feasibility of a telehealth intervention for teaching compensatory cognitive strategies in MS.
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DIGITAL TOOLS Improve Integration of PROs in Oncology
A recent systematic review and meta-analysis found that incorporating PROMs into cancer care is associated with lengthened overall survival and improved QOL.
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Novel AML Classification Helps Identify Older Adults for Curative Treatment
A new classification model called AML60+ improved risk stratification for older adults with acute myeloid leukemia, which can improve clinical decision making.
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Cardiac Catheterization to Diagnose PAH: Tips & Pitfalls, Part 1
A team of cardiologists shared tips and tricks for clinicians to address the pitfalls they may...
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Assessing Itch in Plaque Psoriasis: The Latest Tools & Questionnaires
Dermatologists recently have developed and validated several tools for assessing itch in plaque psoriasis, such as the Peak Pruritus-Numerical Rating Scale.
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Improving Heart Failure Prediction in HCM
The H2FPEF score, a prognostic tool for diagnosing heart failure with preserved ejection fraction, proved useful for risk stratification in HCM.
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Psychosocial Barriers Identified for T2D Management & Coping
Researchers identified six themes, such as awareness of disease and fear of adverse outcomes, as helping or hindering patients in T2D management and coping.
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Self-Management Combo Feasible & Effective for IBS
A recent study demonstrated an online yoga class and a twice-daily probiotic may be an effective combined intervention for managing IBS symptoms.
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Q&A: Panel Offers Actionable Steps Toward Hepatitis C Elimination
Vincent Lo Re III, MD, MSCE, discusses efforts to eliminate the hepatitis C virus in the United States and how to overcome remaining barriers.
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New Approaches to Infection Management for Patients With Burns
Multiple studies published in late 2024 highlight current practices and emerging strategies for infection management for patients with burns.
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Strategies for Improving Guideline-Concordant Care in Lung Cancer
Survival in NSCLC improved with guideline-concordant care in lung cancer, and several factors can be addressed to reach more patients with such care.
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Q&A: Improving PrEP Access in Transgender Men, Other Transmasculine People
Researchers discuss efforts to improve PrEP access in transgender and other transmasculine men who are under-represented in research and prevention efforts.
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MASH With Significant Fibrosis Increases CV Risk, Regardless of Diabetes Status
Liver fibrosis in MASH is linked with elevated risk for cardiovascular events, according to an analysis of NHANES study data.
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