Panel Shows High Sensitivity in MMR Testing for EC
A 2-protein MSH6-PMS2 panel may be a cost-effective, reliable alternative to the 4-protein MMR immunohistochemistry panel in diagnosing MMR deficiency in endometrial cancer.
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Author: Teresa Sellinger
Myectomy Safe in Older Patients With Obstructive HCM
Surgical myectomy was safe in older adults with obstructive hypertrophic cardiomyopathy despite varied morphological features and patient characteristics.
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Family History of RP Linked to Disease Severity at Diagnosis
A family history of retinitis pigmentosa significantly increased the odds of presenting with severe disease, particularly for patients with affected siblings.
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Perceived HIV Risk Low Among People Who Inject Drugs
In general, many people who inject drugs perceive themselves to be at a low risk for HIV despite having indications for pre-exposure prophylaxis use.
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Positive Donor HIV Status Non-Inferior in Kidney Transplant for Patients With HIV
In recipients with HIV, kidney transplant from donors with HIV is noninferior to donors without HIV, with similar rates of AEs and complications.
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Liver Transplant Impacts eGFR in Patients With MASH
Liver transplant impacts post-transplant renal function, specifically eGFR, in patients with metabolic dysfunction-associated steatohepatitis.
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Aerobic Activity Reduces Depression in Patients With Cancer
For adults with cancer, physical activity was associated with a small but significant decline in depression versus usual care, control, or no intervention.
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Preteen Screen Time Impacts Adolescent Mental Health
Screen time in preteens is associated with mental health in adolescence, with the strongest association seen for depressive and conduct symptoms.
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Suicidal Ideation After MS Diagnosis Relatively Common
Suicide ideation is relatively common among patients newly diagnosed with multiple sclerosis, regardless of depression severity.
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Effective Psoriasis Treatment May Curb CV Risk
Early and effective psoriasis treatment may prevent arterial dysfunction and reduce cardiovascular risk even in patients with traditional risk factors.
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NGS Superior to PCR for Detecting EGFR Mutations
Next-generation sequencing outperformed real-time PCR in identifying common and rare EGFR mutations in NSCLC, which could benefit therapy selection.
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Vaccination Less Likely With Social Vulnerability & Black Race
Vaccination for influenza, SARS-CoV-2, and RSV is less likely with greater social vulnerability and Black race, according to findings presented at IDWeek 2024.
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Lungs Stable After HCT for Sickle Cell
Lung function remains stable over 3 years after HCT for sickle cell disease, according to recent research findings by A. Parker Ruhl, MD, MHS, and colleagues.
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Model Predicts Progression to Overt Primary Myelofibrosis
: A model for predicting overt primary myelofibrosis survival in those with prefibrotic primary myelofibrosis showed good predictive ability and clinical value.
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Surgical Refinements Reduce Biliary Complications
Refinement in microsurgical biliary reconstruction techniques has led to a decrease in early biliary complications after living donor liver transplant.
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Low FEF25-75% Increases Risk for Fixed Airflow Obstruction
Low forced expiratory flow at 25%-75% may indicate fixed airflow obstruction in patients with asthma, signaling worse outcomes and need for closer follow-up.
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Model Predicts Lymph Node Metastasis in EC
A clinical-radiomics model predicted lymph node metastasis in type I endometrial cancer with 98% accuracy, outperforming radiomics-only or clinical models.
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Tailoring Exercise for Patients With HCM
Findings suggest a tailored, moderate-intensity exercise program can be safe and beneficial in carefully selected patients with hypertrophic cardiomyopathy.
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Low-Vision-Specific Measures Useful in Assessing RP
Low-vision-specific function and activities of daily living measures are useful for assessing patient-reported outcomes in patients with retinitis pigmentosa.
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PrEP Use Increased From 2013 to 2023
The annual number of PrEP users increased in the United States from 10,281 in 2013 to 505,730 in 2023, primarily in oral formulations.
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