Addressing Non-Adherence & Motivating Patients
For patients with HIV, many factors may influence medication adherence throughout multiple points of their disease course.
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Author: Teresa Sellinger
Encouraging Real-World Results of AHSCT to Treat Aggressive MS
Patients with severe forms of MS had encouraging results with a autologous hematopoietic stem cell transplantation in a large-scale real-world cohort.
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High-Dose Simvastatin Does Not Slow Disability Progression in SPMS
The MS-STAT2 trial of a high-dose simvastatin has failed to slow progression of disability in patients with secondary progressive MS.
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Tolebrutinib Slows Disability Worsening in Relapsing MS
Patients with multiple sclerosis found that their symptoms did not worsen with intake of tolebrutinib, in the GEMINI 1 and 2 studies.
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Why It’s Important to Discuss Sexual Health With Patients
Illness and physical challenges may affect a patient’s ability to engage in sexual activity. For patients with MS, this might be due to fatigue or disability.
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An Easy Way to Identify Disability in Older Adults With RA
Researchers examined the link between LS and grip strength in RA, noting the importance of physical function as a key factor in managing aging populations.
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Empower Patients by Supporting Their Desire for a Second Opinion
Although a patient’s request for a second opinion can make a physician question the patient’s trust level, physicians should consider supporting that desire.
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Fecal Transplants Show Promise in Enhancing Metastatic RCC Treatment
Fecal microbiota transplantation has significantly improved progression-free survival in patients with metastatic renal cell carcinoma.
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Adding Lenvatinib Plus Pembrolizumab to TACE Improves Survival in Intermediate-Stage Hepatocellular Cancer
Lenvatinib plus pembrolizumab has improved survival rates for patients with intermediate-stage hepatocellular cancer, LEAP-012 study finds.
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Adjuvant Durvalumab Does Not Improve Survival in Completely Resected NSCLC
Adjuvant durvalumab did not improve disease-free survival in patients with early-stage non-small cell lung cancer in the phase 3 BR.31 trial.
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High pCR Rates With Dual Neoadjuvant Immunotherapy in TIL-High TNBC
High pathological response rates were seen in patients with triple-negative breast cancer that took two cycles of dual neoadjuvant immunotherapy in phase 2 BELLINI trial.
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Both NICHE-2 & NICHE-3 Trials Show High Efficiency of Short Neoadjuvant Immunotherapy in dMMR Colon Cancer
Patients with dMMR colon cancer in a trial for two neoadjuvant cycles of nivolumab/ipilimumab or nivolumab/relatlimab, had efficiency rates for pathological responses.
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Doublet Maintenance Therapy Does Not Outperform Monotherapy in Ovarian Cancer
Adding nivolumab to rucaparib maintenance therapy did not improve progression-free survival rates in patients with ovarian cancer.
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Emphasizing Societal Benefits of Clinical Trials May Improve Minority Enrollment
Underscoring how trials can benefit all members of a community and discussing spirituality may improve enrollment of Black patients in cancer clinical trials.
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Improving Post-Polypectomy Screening
Fecal immunochemical tests for post-polypectomy colorectal cancer surveillance may reduce the need for colonoscopy and improve screening adherence.
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OCEANIC-AF: Asundexian Does Not Meet Expectations for Stroke Prevention in AF
In the OCEANIC-AF trial, asundexian was found to be inferior to apixaban for stroke prevention in patients with a high risk of stroke and atrial fibrillation.
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ABYSS: Can Beta-Blocker Safely be Interrupted Post-MI?
In the ABYSS trial, researchers found that interrupting a beta-blocker in patients after a myocardial infarction resulted in higher hospitalization rates.
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RHEIA: TAVI Preferred Over Surgery in Women With Aortic Stenosis
The RHEIA trial studied women with severe aortic stenosis and found that participants preferred transcatheter aortic valve replacement over surgical valve replacement.
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Why It’s Important to Discuss Sexual Health with Patients
Sex is an indicator of a healthy lifestyle, so it’s important that physicians discuss sexual health with patients to ensure optimal patient wellness.
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NOTION-3: TAVI Plus PCI Improves Outcomes in CAD Plus Severe Aortic Stenosis
The NOTION-3 study investigated if routine revascularization with PCI and transcatheter aortic valve replacement improves outcomes in patients with stable coronary artery disease and severe aortic stenosis.
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