For patients with benign intracranial meningiomas, single-fraction stereotactic radiosurgery appears to provide a high rate of tumor control. A retrospective review of 416 patients who underwent the procedure found disease-specific survival rates of 97% at 5 years and 94% at 10 years. The local tumor control rates were 96% at 5 years and 89% at 10 years. Negative risk factors for local tumor control included male gender, prior surgery, and tumors located in the parasagittal/falx/convexity regions.
Abstract: Neurosurgery, September 2012.