Analyzing the Relationship Between Allergic Rhinitis, Asthma & Cardiovascular Disease in the National Health Interview Surveys
Atopic disease has been associated with immune dysregulation and chronic inflammation, but current...
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Allergy & Immunology General
Association of the clinical components in the distal interphalangeal joint synovio-entheseal complex and subsequent response to ixekizumab or adalimumab in psoriatic arthritis.
To assess the frequency of simultaneous distal interphalangeal (DIP) joint disease and adjacent nail psoriasis (finger unit) among patients with psoriatic arthritis (PsA) and compare the efficacy of the interleukin (IL)-17A...
Read MoreThe MYC2-PUB22-JAZ4 module plays a crucial role in jasmonate signaling in tomato.
Jasmonates (JAs), a class of lipid-derived stress hormones, play a crucial role across an array of plant physiological processes and stress responses. While JA signaling is generally thought to rely dominantly on the degradation...
Read MorePerceiving E-Cigarettes as Safe and Safer Alternative to Cigarettes Among Young Adults.
Young adults are using e-cigarettes at high rates. While the literature on the health risks associated with e-cigarettes is extensive and growing, little is known about young adults’ thoughts and perceptions of the safety...
Read MoreNo causal association between allergic rhinitis and migraine: a Mendelian randomization study.
Allergic rhinitis (AR) and migraine are among the most common public health problems worldwide. Observational studies on the correlation between AR and migraine have reported inconsistent results. This study aimed to investigate...
Read MoreThe pharmacotherapeutic management of allergic rhinitis in people with asthma.
Up to 90% of asthmatic patients have comorbid allergic rhinitis (AR). Although appropriate therapy of AR can improve asthma symptoms and management, AR is often underdiagnosed and under-treated in asthmatics.A non-systematic...
Read MoreChanges in saliva protein profile throughout Rhipicephalus microplus blood feeding.
When feeding on a vertebrate host, ticks secrete saliva, which is a complex mixture of proteins, lipids, and other molecules. Tick saliva assists the vector in modulating host hemostasis, immunity, and tissue repair mechanisms....
Read MoreA Review of IgA Vasculitis (Henoch-Schönlein Purpura) Past, Present, and Future.
The clinical association of purpura, arthralgia, and arthritis was first described in 1837 in a publication by Johann Lukas Schönlein, a German physician. In 1874, Eduard Henoch, a student of Schönlein, reported cases of...
Read MoreAssociation of antenatal and early childhood air pollution and greenspace exposures with respiratory pathogen upper airway acquisitions and respiratory health outcomes.
The association of air pollution and greenspace with respiratory pathogen acquisition and respiratory health was investigated in a community-based birth-cohort of 158 Australian children. Weekly nasal swabs and daily...
Read MoreSex differences in the tumor promoting effects of tobacco smoke in a cRaf transgenic lung cancer disease model.
Tobacco smoke (TS) is the leading cause for lung cancer (LC), and female smokers are at a greater risk for LC. Yet, the underlying causes are unknown. We performed whole genome scans in TS exposed wild type and histologically...
Read MorePreschool Impulse Oscillometry Predicts Active Asthma and Impaired Lung Function at School Age.
Asthmatic symptoms often start during early childhood. Impulse oscillometry (IOS) is feasible in preschool children who may be unable to reliably perform spirometry measurements.We evaluated the utility of IOS in a multicenter...
Read MoreBlocking CD226 regulates ILC2 effector function and alleviates airway hyperreactivity.
Type 2 innate lymphoid cells (ILC2s) play a pivotal role in type 2 asthma. CD226 is a costimulatory molecule involved in various inflammatory diseases.We aimed to investigate CD226 expression and function within human and mouse...
Read MoreDIA-based quantitative proteomics analysis of plasma exosomes in rat model of allergic rhinitis.
Allergic rhinitis (AR) is a common chronic inflammatory disease characterized by symptoms such as itching, rhinorrhea, sneezing, and nasal obstruction. Despite being classified as an IgE-mediated typeⅠ allergy for many years,...
Read MoreAccess to healthcare among transgender women living with and without HIV in the United States: associations with gender minority stress and resilience factors.
Transgender women (TW) experience significant inequities in healthcare access and health disparities compared to cisgender populations. Access to non-transition related healthcare is understudied among TW. We aimed to assess the...
Read MoreMultidisciplinary-derived clinical score for accurate prediction of long-term mortality in fibrotic lung disease patients.
Idiopathic pulmonary fibrosis (IPF) stands out as one of the most aggressive forms of interstitial lung diseases (ILDs), currently without a definitive cure. Multidisciplinary discussion (MDD) is now considered a cornerstone in...
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Edaravone Shows Protective Effect Against Oxidant Stress
Oxidative stress and endoplasmic reticulum stress (ERS) was associated with the development of...
Read MoreExploring the relationship between allergic contact dermatitis and atopic dermatitis in children: insights from a retrospective patch testing analysis.
Recent years have seen significant exploration into the potential link between allergic contact dermatitis and atopic dermatitis, yielding contradictory findings.A retrospective cohort analysis of children aged 2 to 18 who...
Read MoreDifferent expression levels of interleukin-36 in asthma phenotypes.
Interleukin (IL)-36 family is closely associated with inflammation and consists of IL-36α, IL-36β, IL-36γ, and IL-36Ra. The role of IL-36 in the context of asthma and asthmatic phenotypes is not well characterized. We examined...
Read MoreMechanism of anion exchange and small-molecule inhibition of pendrin.
Pendrin (SLC26A4) is an anion exchanger that mediates bicarbonate (HCO) exchange for chloride (Cl) and is crucial for maintaining pH and salt homeostasis in the kidney, lung, and cochlea. Pendrin also exports iodide (I) in the...
Read MorePosttraumatic stress disorder, trauma, and accelerated biological aging among post-9/11 veterans.
People who experience trauma and develop posttraumatic stress disorder (PTSD) are at increased risk for poor health. One mechanism that could explain this risk is accelerated biological aging, which is associated with the...
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