Parkin, an E3 ubiquitin ligase, enhances airway mitochondrial DNA release and inflammation.
Parkin (Park2), an E3 ubiquitin ligase, is critical to maintain mitochondrial function by...
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Allergy & Immunology General
GRANZYME B CONTRIBUTES TO BARRIER DYSFUNCTION IN OXAZOLONE-INDUCED SKIN INFLAMMATION THROUGH E-CADHERIN AND FILAGGRIN CLEAVAGE.
Atopic dermatitis (AD) is the most common inflammatory skin condition. Skin barrier dysfunction is...
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TLR2 favors OVA-induced allergic airway inflammation in mice through JNK signaling pathway with activation of autophagy.
Numerous studies indicate that toll-like receptor 2 (TLR2) led to divergent effects in asthma. The...
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Patient-Reported Outcomes for Measuring Sleep Disturbance in Pediatric Atopic Dermatitis: cross sectional study of PROMIS Pediatric Sleep Measures and Actigraphy.
Most children with atopic dermatitis(AD) suffer from sleep disturbance, but reliable and valid...
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Immune competence and respiratory symptoms in patients with ataxia telangiectasia: A prospective follow-up study.
Ataxia telangiectasia is a multi-system disorder characterized by progressive cerebellar ataxia,...
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Plasma metabolomic profiles associated with infant food allergy with further consideration of other early life factors.
Fatty acids have been implicated in early life immune development. Food allergy provides a clear...
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The role of education and other transition milestones in the progression of social inequalities in cigarette smoking between the ages of 18 and 25: Evidence from the Canadian National Population Health Survey.
Young adulthood is now considered a sensitive period in the progression of health inequalities...
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Cardiovascular (CV) Benefit of Empagliflozin Across the Spectrum of CV Risk Factor Control in the EMPA-REG OUTCOME Trial.
Control of multiple cardiovascular (CV) risk factors reduces CV events in individuals with type 2...
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Development and Characterization of an Allergic Asthma Rat Model for Interventional Studies.
Allergic asthma is one of the most common chronic diseases of the airways, however it still...
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Elevated Circulating Th2 Cells in Women With Asthma and Psychological Morbidity: A New Asthma Endotype?
Psychological stress shifts the immune system toward the production of T-helper (Th)-2-mediated...
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Elevated testosterone is associated with decreased likelihood of current asthma regardless of sex.
Asthma prevalence decreases post-puberty in males. Testosterone inhibits airway smooth muscle...
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Cow milk protein beta-lactoglobulin confers resilience against allergy by targeting complexed iron into immune cells.
Beta-lactoglobulin (BLG) is a bovine lipocalin in milk with innate defense function. It is not...
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PFAS (per- and polyfluoroalkyl substances) and asthma in young children: NHANES 2013-2014.
Per- and polyfluoroalkyl substances (PFAS) are a class of persistent chemicals used as industrial...
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Sublingual dendritic cells targeting by aptamer: Possible approach for improvement of sublingual immunotherapy efficacy.
The efficacy improvement of current sublingual immunotherapy (SLIT) for preventing and treating...
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Understanding hourly patterns of Olea pollen concentrations as tool for the environmental impact assessment.
Bioinformatics clustering application for mining of a large set of olive pollen aerobiological...
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Food sensitization in preschool Egyptian children with recurrent wheezing.
Food allergy is common in children with prevalence up to 10%. We assessed the clinico-laboratory...
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Self-initiated changes in physical activity and incidence of Metabolic Syndrome: A longitudinal follow-up study.
The aim of this study was to analyze the association between longitudinal physical activity...
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Performance of Viabahn Balloon Expandable Stent (VBX) Compared to Self-Expandable Covered (SES) Stents for Branched Endovascular Aortic Repair.
The objective of this study is to compare the performance between Viabahn balloon-expandable...
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Illustrating the patient journey through the care continuum: Leveraging structured primary care electronic medical record (EMR) data in Ontario, Canada using chronic obstructive pulmonary disease as a case study.
Although barriers exist to secondary use of primary care electronic medical record (EMR) data, the...
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Whole blood transcriptional variations between responders and non-responders in asthma patients receiving omalizumab.
Anti-IgE (omalizumab) has been used for the treatment of moderate-to-severe asthma that is not...
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