Early oral anticoagulation is non-inferior to delayed treatment in patients with ischemic stroke and atrial fibrillation
1. Early DOAC therapy within 4 days was non-inferior to delayed therapy for the composite outcome...
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chronic-disease
Fosrolapitant/Palonosetron in Chemotherapy-Induced Nausea and Vomiting
1. The complete response rate at the overall phase in cycle 1 was 77.7% vs 78.2% with treatment vs...
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Mediterranean diet adherence and risk of diabetes kidney disease
1. In a cohort of patients with hyperglycemia, adherence to a Mediterranean diet (MED) was...
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Cadonilimab plus chemotherapy improves survival in recurrent or metastatic cervical cancer
1. Cadonilimab plus chemotherapy significantly improved progression-free survival in patients with...
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Dyslipidemia contributes to greater incidence of diabetic kidney disease
The ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol is...
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Chronic health conditions and employment transition in childhood-cancer survivors
1. Compared to the general population, survivors of childhood cancer had a greater association...
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1. Isaclimab significantly improved disease activity at 150 mg and 600 mg doses. 2. Adverse events...
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Paretic limbs suffer greater loss of bone mineral density following stroke
1. BMD may differ on paretic and nonparetic sides in stroke patients with a history of falling and...
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Molecular-guided therapy improves survival in unfavorable cancer of unknown primary
1. Patients in the MGT group reported a significantly greater progression-free survival than those...
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Axonal injury may occur up to 9 years prior to symptom onset in multiple sclerosis
1. Multiple sclerosis patients can sustain axonal injury up to 9 years before symptom onset. 2....
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Nivolumab plus Ipilimumab in MSI-High Metastatic Colorectal Cancer
1. Progression-free survival at 12 months was 79% with nivolumab/ipilimumab vs 21% with...
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Use of certain biologics or disease modifying antirheumatic drugs may be associated with cancer risk
1. The use of rituximab, abatacept and Janus kinase inhibitors (JAKis) in individuals with...
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Endometriosis and uterine fibroids associated with a greater risk of mortality due to gynecologic cancers
1. A history of endometriosis and uterine fibroids in women was associated with a greater risk of...
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Amivantumab plus lazertinib improves survival in EGFR-mutated advanced NSCLC
1. In this randomized trial, amivantamab-lazertinib led to significantly longer progression-free...
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#Visual Abstract: Invasive Treatment Strategies Did Not Improve Outcomes for Older Patients with Myocardial Infarction
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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Finerenone reduces heart failure events in patients with HFpEF
1. In this randomized controlled trial of patients with heart failure and mildly decreased or...
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Cases of neurodevelopmental disorders caused by mutated lncRNA CHASERR
1. Three unrelated children were found to have a de novo deletion in the long non-coding RNA...
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Adjuvant dabrafenib and trametinib improve survival in stage III melanoma
1. After almost 10 years of follow-up, adjuvant dabrafenib and trametinib improved relapse-free...
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Early Ramucirumab/Paclitaxel vs Continuation of First-line Chemotherapy in Advanced HER2-negative Gastric/Gastroesophageal Cancer
1. Median PFS was 6.6 months in the switch maintenance group and 3.5 months in the control group...
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Asciminib improves outcomes in chronic myeloid leukemia
1. In this randomized controlled trial, among adults diagnosed with chronic myeloid leukemia...
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