Individualized cancer mRNA-based cancer therapy shows benefit in patients with high-risk melanoma on immunotherapy
1. 18-month recurrence-free survival was significantly greater in the combination therapy group...
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chronic-disease
Pazopanib does not improve disease-free survival post-metastasectomy for renal cell carcinoma patients
1. Pazopanib did not improve disease-free survival in post-metastasectomy renal cell carcinoma...
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Neoadjuvant Chemoimmunotherapy for Lung Cancer – A Meta-Analysis
1. The overall survival had a significant hazard ratio (0.65) when comparing neoadjuvant...
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#VisualAbstract: Liraglutide may improve lower limb perfusion in people with type 2 diabetes and peripheral artery disease
Click here to read this study in JAMA Network Open. ©2024 2 Minute Medicine, Inc. All rights...
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Prophylactic pancreatic stent plus indomethacin reduces rates of pancreatitis following endoscopic retrograde cholangiopancreatography
1. Post-ERCP pancreatitis was more common in the indomethacin alone group compared to indomethacin...
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Adding ribociclib to endocrine therapy appears to improve invasive disease-free survival in patients with early breast cancer
1. Invasive disease-free survival was significantly higher in patients receiving adjuvant...
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Venetoclax monotherapy effectively treats relapsed or refractory chronic lymphocytic leukemia
1. VENICE-1 observed high response rates (complete or partial remission) in both BCRi-naïve and...
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A cell-free, blood-based DNA screening test for colorectal cancer compared to colonoscopy
1. 83.1% of patients with confirmed colorectal cancer had a positive cfDNA test meeting the...
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Immunotherapy vs Chemoimmunotherapy in Older Adults With Advanced NSCLC
1. Adding chemotherapy to immunotherapy did not prolong OS or PFS, with non-significant...
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Cervical intraepithelial neoplasia grade 2 and risk of preterm birth
1. For women with cervical intraepithelial neoplasia grade 2 (CIN2), the risk of preterm birth was...
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Teen pregnancy associated with increased risk of premature mortality in Canada
1. In this cohort study of female teenagers in Ontario, Canada, the risk of premature death was...
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Preoperative breast MRI may reduce need for adjuvant radiotherapy for women with unifocal breast cancer
1. There were similar rates of ipsilateral invasive recurrence among the postoperative adjuvant...
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Poor longterm adherence to surveillance guidelines for childhood cancer survivors in Canada
1. In this retrospective, population-based cohort study, adherence to health surveillance...
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Carbohydrate quality rather than quantity affects risk of colorectal cancer
1. In a large prospective cohort, consumption of higher quality carbohydrates was associated with...
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Imetelstat improves blood transfusion independence in lower-risk myelodysplastic syndromes
1. Significantly more patients in the imetelstat group achieved RBC transfusion independence at 8...
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Biomarkers of Alzheimer’s disease detected as early as 18 years prior to diagnosis
1. In this case-control study, cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease...
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Baricitinib preserves beta cell function in new-onset type 1 diabetes
1. In this randomized controlled trial, baricitinib, a Janus kinase (JAK) inhibitor, preserved...
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Obesity may be a risk factor for stillbirth during pregnancy
1. Pregnant individuals with obesity according to their body mass index (BMI) had an increased...
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Seladelpar improves symptoms of primary biliary cholangitis
1. In this randomized controlled trial, among patients with primary biliary cholangitis (PBC) who...
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Elafibranor associated with biochemical response in patients with primary biliary cholangitis
1. In this randomized controlled trial, primary biliary cholangitis (PBC) patients who received...
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