Statins may improve tolerability of antidepressant therapy
1. In a large population-based cohort study, combination therapy of antidepressant therapy with a...
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chronic-disease
Sarilumab increases remission rate in patients with polymyalgia rheumatica relapse
1. In this randomized controlled trial, patients with polymyalgia rheumatica (PMR) flares who...
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Repeat transcatheter aortic valve replacement after initial attempt is generally safe in patients with balloon-expandable valves
1. Redo-TAVR had low procedural complication rates and was comparable to native-TAVR in terms of...
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Chronic high-intensity interval training and moderate-intensity continuous training increase maximum fat oxidation in adults with overweight and obesity
Bookmark1. In this meta-analysis, both high-intensity interval training and moderate-intensity...
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Dexamethasone does not improve tuberculous meningitis survival in HIV
Bookmark1. In this randomized controlled trial, compared to placebo, dexamethasone did not improve...
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Optical coherence tomography guidance beneficial for managing coronary bifurcation lesions
Bookmark1. In this randomized controlled trial, percutaneous coronary intervention (PCI) performed...
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Spesolimab may improve quality of life in patients with generalized pustular psoriasis flares
Bookmark1. Efficacy of spesolimab appeared to be dose-dependent with high-dose spesolimab leading...
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Concurrent stereotactic radiation with antibody-drug conjugates in the treatment of brain metastases is associated with a greater risk of symptomatic radiation necrosis
Bookmark1. A greater percentage of patients who received concurrent stereotactic radiation therapy...
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Amivantamab Plus Chemotherapy with and without Lazertinib in EGFR-mutant NSCLC
Bookmark1. Progression-free survival was 6.3 months for the amivantamab–chemotherapy group, 8.3...
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Esketamine augmentation therapy is superior to quetiapine for treatment-related depression
Bookmark1. In this randomized controlled trial, in patients with treatment-resistant depression...
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Tight versus liberal blood glucose control results in similar ICU outcomes
Bookmark1. In this randomized controlled trial, tight versus liberal blood glucose control...
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Semaglutide improves symptoms in patients with heart failure
Bookmark1. In this randomized controlled trial, in patients with heart failure with preserved...
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Solanezumab does not slow cognitive decline in patients with Alzheimer’s disease
Bookmark1. In this randomized controlled trial, over a period of 240 weeks, solanezumab did not...
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Recovery of knee function from total knee arthroplasty associated with improvement in depression symptoms
Bookmark1. Total knee arthroplasty was found to decrease the incidence of depression among...
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Sacituzumab govitecan shows survival benefit in endocrine-resistant hormone-positive metastatic breast cancer
Bookmark1. Median overall survival increased by 3.2 months in the sacituzumab govitecan group...
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Spiritual intelligence may be associated with self-management of type 1 diabetes
Bookmark1. In this cross-sectional study, spiritual intelligence was a significant predictor of...
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Avacincaptad pegol reduces the rate of age-related macular degeneration in geographic atrophy
Bookmark1. Avacincaptad pegol significantly slowed geographic atrophy over 12 months. 2. Exudative...
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Factors important for health-related quality of life in men and women
Bookmark1. This cross-sectional study found that physical activity, employment, pain, and sense of...
Read MoreSelpercatinib vs Chemotherapy and Pembrolizumab in RET Positive NSCLC
Bookmark1. The progression-free survival was 24.8 months in the selpercatinib group vs 11.2 months in the control group (chemotherapy ± pembrolizumab), with an HR of 0.46. 2. Grade ≥3 adverse events occurred in 70% vs 57%...
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Extracorporeal membrane oxygenation increases bleeding risk in patients with cardiogenic shock
Bookmark1. 30-day mortality was comparable among patients on VA-ECMO and medical therapy alone. 2....
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