Severe premenstrual disorder may increase risk of early onset perimenopausal symptoms
Bookmark1. This prospective study found that women with severe premenstrual disorders (PMDs) were...
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chronic-disease
Tumor Treating Fields vs Standard Therapy in Treatment-Resistant Metastatic NSCLC
Bookmark1. The median OS was 13.2 months with TTFields arm vs 9.9 months with standard arm, with...
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Cognitive behavioural therapy effective for fibromyalgia pain
Bookmark1. This randomized controlled trial found that an 8-week cognitive behavioural therapy...
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Obstructive sleep apnea and vitamin D deficiency are closely linked
Bookmark1. In this systematic review and meta-analysis, patients with obstructive sleep apnea...
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Cetuximab maintenance therapy may be effective for RAS Wild-type metastatic colorectal cancer
Bookmark1. This phase 2 randomized clinical trial found that patients with metastatic colorectal...
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Evening chronotype in middle-aged nurses is associated with an increased diabetes risk
Bookmark1. In this prospective cohort study, middle-aged nurses with an evening chronotype were...
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Adjuvant nivolumab may be promising for treatment of completely resected Merkel cell carcinoma
Bookmark1. Disease-free survival at 24 months was 84% in the nivolumab group compared to 73% in...
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Non-erosive gastro-oesophageal reflux disease not associated with increased incidence of oesophageal adenocarcinoma
Bookmark1. Patients with non-erosive gastro-esophageal reflux disease (GERD) do not have an...
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Pegozafermin associated with improved outcomes in nonalcoholic steatohepatitis
Bookmark1. In this randomized controlled trial, treatment with pegozafermin improved fibrosis in...
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Atogepant may be safe and effective for prevention of chronic migraines
Bookmark1. Monthly migraine days were significantly reduced in atogepant 30 mg twice daily and...
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Mortality risk higher after the first occurrence of osteoporotic vertebral compression fractures
Bookmark1. Patients with a new diagnosis of osteoporotic vertebral compression fracture (OVCF) are...
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Low achievement of guideline-recommended diabetes targets in Chinese adults
1. In this cross-sectional study, the proportion of Chinese adults with self-reported type 2...
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High-dose oral semaglutide effectively glycemic control in patients with type 2 diabetes mellitus
Bookmark1. HbA1c reduction was dose-dependent in the semaglutide group with the greatest change...
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Combined digital intervention may be effective for osteoarthritis pain
Bookmark1. Following total knee replacement (TKR) for osteoarthritis, patients randomized to a...
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Atezolizumab is a potentially effective treatment option for patients with alveolar soft part sarcoma
Bookmark1. 37% of study patients had an objective response to treatment with atezolizumab. 2....
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Patritumab Deruxtecan in EGFR-mutated NSCLC post EGFR TKI and Chemotherapy
Bookmark1. The objective response rate was 29.8% (1% complete response, 66% partial response) with...
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Generic and brand-name fluticasone-salmeterol are equally effective in COPD management
Bookmark1. In this cohort study, using generic versus brand-name fluticasone-salmeterol was...
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Rectal cancer presentation and screening rates during the COVID-19 pandemic
Bookmark1. Despite the decrease in colonoscopies performed at the start of the COVID-19 pandemic,...
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Adjunctive antidepressant maintenance ineffective in bipolar I depression
Bookmark1. In this randomized controlled trial, adjunctive treatment with escitalopram or...
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Oral semaglutide effectively reduces bodyweight in non-diabetic adults with obesity
Bookmark1. The semaglutide 50 mg group saw a 15.1% reduction in body weight at 68 weeks compared...
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