CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages
Bookmark1. Compared to healthy controls, participants with a first episode of schizophrenia had...
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chronic-disease
Dupilumab reduces the number exacerbations in patients with COPD and type two inflammation
Bookmark1. In this randomized controlled trial, dupilumab use was associated with significantly...
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Dupilumab For Management of Bullous Pemphigoids
Bookmark1. Dupilumab treatment for bullous pemphigoids resulted in improved clinical symptoms. 2....
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School-based water promotion program associated with lower overweight prevalence
Bookmark1. Implementation of ‘Water First’, a program consisting of classroom lessons, water...
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Zilebesiran improves blood pressure management in patients with hypertension
Bookmark1. In this randomized controlled trial, zilebesiran resulted in reduced serum...
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Opioid analgesia may be ineffective for acute low back and neck pain
Bookmark1. Mean pain score at 6 weeks was not statistically different between the opioid and...
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Mortality rates among patients successfully treated for hepatitis C still higher than the general population
Bookmark1. Among those treated for Hepatitis C Virus (HCV) infection, leading causes of death...
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Long-acting antiretroviral therapy injections maintain viral suppression in people living with HIV
Bookmark1. In this observational study, long-acting antiretroviral therapy (LA-ART) was effective...
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Talazoparib plus enzalutamide improves progression-free survival in metastatic prostate cancer
Bookmark1. Progression-free survival was significantly higher in the talazoparib plus enzalutamide...
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Reducing the screening age for colorectal cancer in Canada to 40 or 45 may result in fewer cases, less mortality, and reduced healthcare spending costs
Bookmark1. Initiating colorectal cancer screening at age 45 results in 12,188 fewer cases and...
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Integrated Clinical-Molecular Classification of Colorectal Liver Metastases
Bookmark1. The immune subtype demonstrated an improved progression-free survival (HR 0.37) and...
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Insulin icodec is more effective than insulin glargine for glycemic control
Bookmark1. In this randomized controlled trial, weekly insulin icodec use resulted in better...
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SGLT2 inhibitors reduce recurrent flares and hospitalizations in patients with gout
Bookmark1. In this population cohort study, patients with gout who used sodium-glucose...
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Social screening in community health clinics does not consistently improve early childhood health
Bookmark1. In a randomized control trial of the social care screening program WE CARE, health...
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Atezolizumab added to cabozantinib does not improve clinical outcomes in patients with metastatic renal cell carcinoma
Bookmark1. Progression-free and overall survival was comparable in both the intervention and...
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Double-balloon enteroscopy for the evaluation of symptomatic small bowel stricture in Crohn’s disease
Bookmark1. Double-balloon enteroscopy (DBE) has a high diagnostic yield for small-bowel strictures...
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Increased physical activity may reduce the incidence of type 2 diabetes mellitus irrespective of genetic risk
Bookmark1. In this prospective cohort study, it was found that those with the highest levels of...
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There is a low risk of chronic kidney disease progression following acute kidney injury
Bookmark1. In this prospective cohort study, there was a limited association between acute kidney...
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Intranasal etripamil effective for conversion of paroxysmal supraventricular tachycardia
Bookmark1. Median time to sinus conversion was 17.2 minutes in the etripamil group versus 53.5...
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History of delirium tremens associated with greater mortality and morbidity risk than alcohol dependence alone
Bookmark1. Patients with a history of treated delirium tremens (DT) are at higher risk for...
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