Aerobic-resistance exercise is an effective adjunct for improving cognition in mild cognitive impairment
Bookmark1. Patients with mild cognitive impairment (MCI) randomized to a combined intervention of...
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chronic-disease
Internet delivered emotion regulation individual therapy effective as an adunct to reduce nonsuicidal self-injury
Bookmark1. Internet-delivered emotion regulation for adolescents (IERITA) used in combination with...
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Double-balloon endoscopy for the evaluation of symptomatic small bowel stricture in Crohn’s disease
Bookmark1. Double-balloon enteroscopy (DBE) has a high diagnostic yield for small-bowel strictures...
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Ticagrelor-acetylsalicylic acid may reduce stroke risk further for obese patients than clopidogrel
Bookmark1. For obese patients with minor stroke or transient ischemic attacks (TIA), subsequent...
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Fruquintinib significantly improves survival in patients with refractory metastatic colorectal cancer
Bookmark1. Overall survival was significantly greater in the fruquintinib group versus placebo. 2....
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Internet delivered emotion regulation individual therapy effective as an adjunct to reduce nonsuicidal self-injury
Bookmark 1. Internet-delivered emotion regulation for adolescents (IERITA) used in combination...
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Low-molecular-weight heparin does not improve live birth rates in women with recurrent pregnancy loss and thrombophilia
Bookmark1. Live birth rate between the low-molecular-weight heparin and standard care group was...
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Checkpoint Inhibitors With Radiotherapy in Patients With Advanced Solid Tumors
Bookmark1. Stereotactic body radiotherapy in addition to immune checkpoint inhibitors has similar...
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Long telomere syndrome is associated with an increased risk of developing neoplasms
Bookmark1. In this case series, protection of telomeres 1 (POT1) mutations associated with long...
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Buleviritide reduces viral load in patients with chronic hepatitis D
Bookmark1. In this randomized controlled trial, 48 weeks of buleviritide treatment resulted in...
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Hyperlipidemia may be associated with greater risk of stenosing tenosynovitis
Bookmark1. In a large Taiwanese cohort, it was found that patients with hyperlipidemia had higher...
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Some sleep problems are associated with multimorbidity
Bookmark1. In this systematic review and meta-analysis, short sleep duration, long sleep duration,...
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Adjuvant treatment with programmed cell death receptor-1 inhibitor pembrolizumab is an effective adjuvant treatment for stage III/IV melanoma
Bookmark1. Five-year disease-free survival was greater in patients who had ≤10% viable tumour or...
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Ketamine noninferior to ECT for symptom management in treatment-resistant major depression
Bookmark 1. In this randomized controlled trial, ketamine was noninferior to electroconvulsive...
Read MoreDolutegravir noninferior to a ritonavir-boosted protease inhibitor regimen for treating HIV
Bookmark1. In the randomized controlled trial, dolutegravir treatment was noninferior to a regimen containing a ritonavir-boosted protease inhibitor (PI) for treating human immunodeficiency virus (HIV). 2. Dolutegravir...
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Gemcitabine and docetaxel combination in relapsed metastatic or unresectable locally advanced synovial sarcoma
Bookmark1. Combination therapy with gemcitabine and docetaxel for patients with metastatic or...
Read MoreYounger age may be a poor prognostic factor in patients with metastatic colon cancer
Bookmark1. In this retrospective cohort study, patients younger than 50 with metastatic colorectal cancer (mCRC) had significantly shorter progression-free survival and overall survival rates compared with those aged 50 to 65...
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A dual-chamber leadless pacemaker provided reliable long-term atrioventricular synchrony
Bookmark1. In the prospective study, a dual-chamber leadless pacemaker system met primary safety...
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Cyclophosphamide-tacrolimus-mycophenolate mofetil is an effective prophylaxis against graft-versus-host disease
Bookmark1. In this randomized controlled trial, cyclophosphamide-tacrolimus-mycophenolate mofetil...
Read MoreDose-escalated simultaneous integrated boost radiotherapy may increase ipsilateral breast tumor relapse rates
Bookmark1. 5-year ipsilateral breast tumor relapse rates for test group 1 were non-inferior to the control group. However, noninferiority was not shown with test group 2 versus control. 2. Test group 2 was found to have a higher...
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