Tirzepatide reduces obstructive sleep apnea symptoms and associated risks
1. In this randomized controlled trial, in patients with both moderate-severe obstructive sleep...
Read More
chronic-disease
DaxibotulinumtoxinA trial for injection for the treatment of upper limb spasticity in adults after stroke or traumatic brain injury
1. DaxibotulinumtoxinA-lanm 500U showed the greatest reduction in MAS scores in patients suffering...
Read More
Fidanacogene elaparovovec may reduce bleeding in men with hemophilia B
1. In this randomized controlled trial, fidanacogene elaparovovec therapy significantly reduced...
Read More
Liver Transplantation + Chemo Improves Survival for Unresectable Colorectal Liver Metastases
1. 5-year survival was significantly greater in the liver transplantation plus chemotherapy group...
Read More
Double dose extracorporeal shockwave may be more effective for plantar flexor spasticity of ankle in stroke patients
1. Double-dose ESWT to the gastrocnemius and soleus showed greater improvements in post-stroke...
Read More
Electronic health record-based programs can increase screening for intimate partner violence
1. In a cluster randomized clinical trial, electronic health record (EHR)-based intervention...
Read More
Cabozantinib In Advanced Neuroendocrine Tumors
1. Progression-free survival had a hazard ratio of 0.38 (extrapancreatic NETs) and 0.23...
Read More
Crinecerfont Decreases Glucocorticoid Use in Adults With Congenital Adrenal Hyperplasia
1. In this randomized controlled trial, twice daily crinecerfont use was associated with reduced...
Read More
Predicting adherence to gamified cognitive training using early phase game performance data
1. Just-in-time adherence support systems in gamified cognitive training should be applied when...
Read More
Body roundness index may help estimate cardiovascular disease
1. A higher body roundness index (BRI) trajectory is associated with an increased risk of...
Read More
Neuroprosthesis enables conversational communication in amyotrophic lateral sclerosis
1. A participant with amyotrophic lateral sclerosis (ALS) and severe dysarthria underwent surgical...
Read More
History of Mild TBI Linked to Detectable Neuroimaging Changes, Depressive Symptoms, & Poorer Sleep
1. A history of mild traumatic brain injury (TBI) in healthy, middle-aged adults was associated...
Read More
Tulisokibart Induces Clinical Remission in Moderate-to-Severely Active Ulcerative Colitis
1. In this randomized controlled trial, among patients with moderately to severely active...
Read More
Digital cognitive therapy program may be effective for alcohol use disorder
1. In this randomized clinical trial, adults with an alcohol use disorder (AUD) receiving either...
Read More
Optical coherence tomography-guided angioplasty reduces adverse events compared to angiography guidance
1. Major cardiac events were significantly lower in the OCT-guided group compared to the...
Read More
Phase II basket trial of dual anti-CTLA-4 and anti-PD-1 blockade in rare tumors
1. Treatment of desmoid tumours with dual anti-CTLA-4 and anti-PD-1 blockade with ipilimumab and...
Read More
Overall Survival with Pembrolizumab in Early-Stage Triple-Negative Breast Cancer
1. The 5-year OS rate for pembrolizumab vs placebo was 86.1% vs 81.7% with HR 0.51 (significant)....
Read More
Time-Restricted Eating May Improve Glycemic Regulation in Metabolic Syndrome
1. In this randomized controlled trial, patients with metabolic syndrome who underwent...
Read More
Infusion with a monoclonal antibody decreases migraine frequency
1. In this randomized controlled trial, in patients diagnosed with migraine, it was found that...
Read More
Ticagrelor monotherapy reduces bleeding risk compared to dual antiplatelet therapy for patients following coronary stenting
1. Ticagrelor was non-inferior to DAPT for the incidence of major adverse cardiovascular and...
Read More