TKI With or Without SRS for Brain Metastases From EGFR/ALK Mutated NSCLC
1. Median overall survival was 41 months in the TKI-only group vs 40 months in the TKI-SRS group,...
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chronic-disease
Comparing Burr-Hole Drainage With or Without Subdural Irrigation for Chronic Subdural Hematoma
1. Patients who underwent burr-hole drainage with subdural irrigation had fewer reoperation rates...
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Overground robot-assisted gait training may be effective in children with cerebral palsy
1. Overground Robot-assisted gait training (RAGT), using a new torque-assisted wearable...
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Sintilimab improves survival in advanced non-metastatic nasopharyngeal carcinoma
1. Patients in the sintilimab group reported a significantly greater event-free survival at 36...
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Use of fluoroquinolones and may increase the risk of aortic and mitral regurgitation
1. Patient data from a Taiwanese national database demonstrated that those who took...
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Efanesoctocog alfa in children with hemophilia A reduces bleeding
1. In this randomized controlled trial, a prophylactic weekly dose of efanesoctocog alfa...
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Cyclophosphamide may be an effective treatment for myalgic encephalomyelitis
1. Six-year follow-up data reveal that ME/CFS patients treated with cyclophosphamide reported...
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Hormone-modulating therapy decreased risk of dementia in breast cancer patients
1. In a retrospective cohort study of women newly diagnosed with breast cancer, use of hormone...
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Emergency departments likely overprescribing opioids for acute pain
1. In this cohort study, majority of the participants did not use all of the opioids prescribed to...
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Vimseltinib may be promising in treating symptomatic tenosynovial giant cell tumour
1. Tumor response rate at 25 weeks was significantly greater in vimseltinib than placebo. 2. Most...
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Intravenous tenecteplase shows no benefit in minor ischemic stroke with intracranial occlusion
1. Return to baseline function was comparable in tenecteplase and standard-of-care groups. 2. More...
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Multi-Organ Immune-related Adverse Events from Immune Checkpoint Inhibitors
1. Co-occurrences could be clustered together into 7 clusters based on the predominant organ...
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Benralizumab associated with histologic response in eosinophilic esophagitis
1. In this randomized controlled trial, benralizumab, an anti-interleukin-5 receptor (anti-IL-5R)...
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Tisotumab Vedotin as Second or Third-Line Therapy for Recurrent Cervical Cancer
1. Median overall survival was 11.5 months in the tisotumab vedotin group and 9.5 months in the...
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Oral sebetralstat provides early symptom relief for hereditary angioedema attacks
1. In this randomized controlled trial, oral sebetralstat provided faster times to the beginning...
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Web-based cognitive behavioural therapy may be effective for treatment of bulimia nervosa
1. Patients with bulimia nervosa randomized to receive web-based cognitive behavioural therapy...
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Financial incentives may be a viable option to promote smoking cessation
1. Incentivizing smoking cessation with financial rewards increased the likelihood of cessation...
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Poor cardiovascular health is a risk factor for female infertility
1. Cardiovascular health and infertility are negatively correlated with physical activity, BMI,...
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Periodontitis in patients with diabetes and its association with diabetes-related complication
1. Periodontitis has a strong association with Type 2 Diabetes and is exacerbated by poor glycemic...
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Immunotherapy-Based Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer
1. The complete response rates (pathological and clinical) were similar (~55%) in both groups. 2....
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