Combined genetic testing of cardiomyopathies and arrhythmias increases diagnostic yield to inform patient management
1. Comprehensive genetic testing for cardiomyopathy and arrhythmia diagnoses improved the ability...
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chronic-disease
Prasinezumab therapy does not affect Parkinson’s Disease progression
1. Prasinezumab had no meaningful effect on global or imaging measures of Parkinson’s disease...
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Graded sensorimotor retraining may improve chronic lower back pain compared to sham procedure: The RESOLVE randomized clinical trial
1. This randomized clinical trial demonstrated that among 276 adult patients with moderate to...
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Genetic risk for hemochromatosis associated with abnormal iron deposition localized to motor circuits of the brain
1. This retrospective cross-sectional study found that among 836 individuals at high genetic risk...
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Racial differences exist in emphysema prevalence in adults with normal spirometry findings
1. Black men are more likely than White men to have emphysema with normal spirometry findings. 2....
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Moderate-intensity statin plus ezetimibe is non-inferior to high-intensity statin monotherapy
1. 3-year composite outcome of stroke and cardiovascular disease was comparable between both...
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Monoclonal antibody L9LS prevents malaria infection in adults
1. In this small phase one clinical trial, L9LS administration protected healthy adults from...
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Baricitinib reduces mortality risk in patients hospitalized with COVID-19
1. Baricitinib with usual care was associated with a 13% proportional reduction in mortality...
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Methamphetamine use associated with cardiovascular disease in hospitalized patients
1. Among hospitalized patients, methamphetamine use was associated with an increased risk of...
Read More![Endovaginal ultrasound highly sensitive screen for endometrial cancer [Classics Series]](https://cdn.physiciansweekly.com/wp-content/uploads/2022/08/image1660130795.jpg)
Endovaginal ultrasound highly sensitive screen for endometrial cancer [Classics Series]
This study summary is an excerpt from the book 2 Minute Medicine’s The Classics in Medicine:...
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Germline Mutations in CIDEB Confer Protection from Liver Disease
1. Rare mutations in CIDEB are associated with a decreased risk of developing liver cirrhosis. 2....
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Nonsteroidal Anti-Inflammatory Drug exposure associated with development of microscopic colitis
1. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) were independently associated with the...
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Litifilimab associated with reduced disease severity in patients with cutaneous lupus erythematosus
1. Litifilimab significantly decreased cutaneous lupus erythematosus (CLE) disease area and...
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Gout flares associated with a transient increase in subsequent risk of cardiovascular events
1. Amongst patients with gout, those who experienced a cardiovascular event were likely to have...
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Supplemental vitamin D does not reduce risk of fractures in older adults
1. There were no significant differences in total, non-vertebral, or hip fractures between the...
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Atherosclerotic risk factors associated with stroke in adulthood present from childhood and increase with age
1. Atherosclerotic risk factors associated with stroke later in life were present in children, but...
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Vaccination after recovery from COVID-19 reduced rate of reinfection by half
1. Completion of the primary vaccination series against COVID-19 amongst individuals who had...
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Comprehensive telehealth intervention effective for reducing HbA1c in poorly controlled diabetes
1. In this randomized controlled trial, a comprehensive telehealth intervention was linked to a...
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Methotrexate reduces functional burden of disease in patients with arthralgia at-risk of developing rheumatoid arthritis
1. Compared to placebo, methotrexate did not significantly reduce the risk of the development of...
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Association between early left ventricular ejection fraction improvement after transcatheter aortic valve replacement and 5-Year clinical outcomes
1. In this retrospective cohort study, left ventricular ejection fraction (LVEF) improvement at 30...
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