Adjuvant erlotinib increased overall survival when compared to chemotherapy in stage IIIA EGFR-mutant non-small cell lung cancer
1. Erlotinib showed an overall survival benefit and improved 5-year survival rates when compared...
Read More
chronic-disease
Sacituzumab govitecan may be an effective treatment for heavily pre-treated HR+/HER2- metastatic breast cancer.
1. Median progression-free survival was longer in the SG group than in the chemotherapy group. 2....
Read More
Physical function as a predictor for cardiovascular disease risk in the elderly
1. A higher physical function among community-dwelling older adults was associated with a...
Read More
Remote ischemic conditioning associated with better neurologic function in patients with acute moderate ischemic stroke – the RICAMIS trial
1. In this randomized clinical trial, among 1893 patients with acute moderate ischemic stroke,...
Read More
Reinfection with hepatitis C virus is highest immediately after treatment in patients on opioid agonist therapy
1. Reinfection with hepatitis C virus (HCV) was highest in the first 24 weeks after treatment...
Read More
Effectiveness of self-monitoring blood pressure program with smartphone application
1. A self-monitoring blood pressure (SMBP) program enhanced with smartphone patient engagement...
Read More
The influence of body-mind-spirit interventions on well-being may be poorly understood
1. Few studies included all concepts of the Body-Mind-Spirit (BMS), including detailed...
Read More
Youth-onset type 2 diabetes may have increased sharply during the COVID-19 pandemic
1. In a retrospective cohort of about 3,000 children and young adults, new diagnoses of type 2...
Read More
Ublituximab lowers incidence of relapse and number of brain lesions in relapsing multiple sclerosis
1. Two randomized clinical trials showed that intravenous ublituximab reduced relapse rate and the...
Read More
Olokizumab is noninferior to adalimumab for the treatment of rheumatoid arthritis
1. Olokizumab was superior to placebo in improving rheumatoid arthritis (RA) symptoms. 2....
Read More
Childhood cash supplementation program may improve outcomes into adulthood
1. In this longitudinal cohort study assessing the benefits of a cash supplementation program in...
Read More
Statin use provide effective primary prevention against cardiovascular disease in high-risk patients – US Preventive Services Task Force
1. Statin use in patients at increased risk of cardiovascular disease without prior history of...
Read More
Mepolizumab reduced exacerbations in children with exacerbation-prone eosinophilic asthma
1. There was a 27% reduction of severe asthma exacerbations in children treated with mepolizumab...
Read More
Mitapivat may improve anemia in adults with non-transfusion dependent α- and β-thalassemia
1. 80% of patients receiving mitapivat showed hemoglobin response at 12 weeks. 2. Markers of...
Read More
Switching from cigarettes to e-cigarette alternatives not associated with improvement in cardiovascular outcomes
1. An improvement in cardiovascular disease (CVD) outcomes was found at 3 months and 6 months...
Read More
Fazirsiran is associated with decreased levels of misfolded alpha1-antitrypsin protein
1. Patients on fazirsiran had reductions in total liver misfolded alpha1-antitrypsin protein...
Read More
Chronic kidney disease associated with increased risk of spontaneous intracranial hemorrhage
1. Chronic kidney disease was independently associated with an increased risk of spontaneous...
Read More
Hospitalization due to COVID-19 increases risk of venous thromboembolism compared to hospitalization due to influenza
1. Patients hospitalized due to COVID-19 had a higher risk of developing a venous thromboembolism...
Read More
Co-use of methamphetamine and opioids associated with higher rates of nonfatal overdoses compared to independent use
1. This cross-sectional study using survey data from individuals in US states with high overdose...
Read More
Newborn screening for cystic fibrosis improves nutritional outcomes
1. In this retrospective study, newborn screening for cystic fibrosis in the United States lead...
Read More