Association Between CYP Metabolizer Phenotypes and SSRI Induced Weight Gain
1. In this retrospective cohort study, in patients prescribed citalopram, poor/intermediate...
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chronic-disease
Demographic trends in heart failure related mortality over past 2 decades
1. In this retrospective cohort analysis, heart failure (HF) related mortality has increased in...
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Dapagliflozin associated with reduced risk of cardiovascular and kidney outcomes irrespective of background use of cardiovascular medications
1. In this secondary analysis of the DECLARE-TIMI 58 trial, among 17,160 patients, dapagliflozin...
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Exposure to macrolides in children may be potentially associated with sensorineural hearing loss
1. Patients under 18 years of age with sensorineural hearing loss (SNHL) had a higher odds of...
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Use of left ventricular assist device associated with increased mortality compared to intra-aortic balloon pump in patients with cardiogenic shock from myocardial infarction
1. Use of an intravascular left ventricular assist device was associated with higher mortality in...
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Omecamtiv mecarbil not associated with improved exercise capacity compared with placebo in patients with chronic heart failure with reduced ejection fraction
1. In this randomized controlled trial, among 276 patients with chronic heart failure with reduced...
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Alcohol recovery narratives are dynamic and may be composed of multiple dimensions
1. In this study, the eight principle narrative dimensions related to alcohol recovery identified...
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Pembrolizumab plus chemotherapy improved survival in a subgroup of triple-negative metastatic breast cancer
1. Pembrolizumab plus chemotherapy for triple-negative breast cancer significantly increased PFS...
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Low-dose AAVS3 gene therapy is efficacious for treating patients with hemophilia B
1. Hemophilia B patients treated with the adeno-associated virus (AAV) gene therapy produced...
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Wishes and needs of nursing home residents are heterogeneous and comprise various themes
1. Wishes and needs of nursing home residents were assigned to 12 different themes, the most...
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Uptake of hepatitis C treatment in people who inject drugs associated with decreased liver disease
1. Hepatitis C patients with undetectable hepatitis C virus (HCV) RNA had reduced liver disease...
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Cardiac magnetic resonance imaging accurately assessed left ventricular end systolic volume in patients with remodeling due to chronic aortic regurgitation
1. In this retrospective cohort study, the degree of symptom burden correlated well with left...
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Pharmacotherapy is effective for acute insomnia but with worse side effect profiles than placebo
1. Eszopiclone and Lemborexant were more efficacious for acute and long-term insomnia compared to...
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Religious and spiritual practices may improve mental health in older adults
1. In the present systematic review and meta-analysis, high religious and spiritual (RS) practices...
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Topical hypericin photodynamic therapy is effective and safe in early-stage T cell lymphoma
1. Hypericin photodynamic therapy was found to be more efficacious in treating early-stage T cell...
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Intravenous tenecteplase non-inferior to alteplase for thrombolysis in acute ischemic stroke
1. IV tenecteplase was non-inferior to IV alteplase for treatment of acute ischemic stroke...
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Long‐term outcomes of pulmonary vein isolation in patients with Brugada Syndrome and paroxysmal atrial fibrillation
1. At 58 months follow-up, fewer patients with Brugada Syndrome (BrS) and associated paroxysmal...
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Understanding purpose in life in older adults may require a multifaceted approach
1. In this systematic review, purpose in life was conceptualized as: health and well-being,...
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Tirzepatide reduces body weight and improves cardiometabolic function in patients with obesity
1. Tirzepatide treatment significantly reduced body weight and fat composition in obese patients...
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Incidence and predictors of multimorbidity in a Korean geriatric population
1. The incidence of multimorbidity increased with age amongst the Korean geriatric population. 2....
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