Sickle cell trait associated with preexisting kidney comorbidities and increased COVID-19 mortality
1. Sickle cell trait was associated with increased COVID-19 mortality and various preexisting...
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chronic-disease
Cognitive behavioral therapy efficacious for treatment of comorbid posttraumatic headache and posttraumatic stress disorder symptoms among US veterans
1. Among US military veterans with posttraumatic headache and comorbid posttraumatic stress...
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Early exposure to allergenic foods may reduce incidence of long-term food allergy
1. Prevalence of food allergy at 36 months was greatest in the skin intervention group and lowest...
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Lisocabtagene maraleucel improves survival for relapsed or refractory large B-cell lymphoma
1. Median event-free survival in the liso-cel group was significantly greater than in the...
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ACKR1 variant increases risk of azathioprine-related hematopoietic toxicity
1. Patients with the ACKR1 variant (CC genotype) had an elevated risk of azathioprine...
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Heavy smoking is associated with visual field loss in glaucoma
1. In a cohort of about 500 eyes with primary open-angle glaucoma (POAG), higher smoking intensity...
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Post-operative opioids at discharge increase adverse events without improving pain management
1. There was no significant difference in pain reduction among patients in the opioid and...
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United States medical cannabis registration increased significantly between 2016 and 2020
1. Registration for medical cannabis increased 4.5 times from 2016 to 2020 in the United States,...
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Fazirsiran reduces Z-AAT protein production in alpha1-antitrypsin deficiency
1. Fazirsiran is associated with a signifcant reduction of Z-AAT protein concentration in the...
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2 Minute Medicine Rewind June 27, 2022
Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A...
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High tumour mutation burden in NSCLC associated with improved clinical outcomes of PD-L1 blockade across PD-L1 expression subgroups
1. High tumour mutation burden levels were associated with improvements in objective response...
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Treatment of anal high-grade squamous intraepithelial lesions can reduce rates of progression to invasive anal cancer.
1. The rate of progression was 57% lower in the group receiving anal HSIL treatment as compared to...
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Human papillomavirus (HPV) vaccination rates have increased in recent years
1. Between 2015 and 2020, human papillomavirus vaccination (HPV) rates in the United States...
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CYP2C19 loss-of-function carriers have modest benefit from ticagrelor and aspirin following cerebrovascular event: CHANCE-2 Trial
1. Patients carrying the CYP2C19 loss-of-function mutation (C-LOF), who had experienced a minor...
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Children with complex chronic conditions represent approximately half of postoperative deaths in children undergoing tonsillectomy in 5 US states
1. Among children undergoing tonsillectomy, the rate of postoperative death was 7 per 100 000...
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Incidence of Kawasaki disease found to be lower during the COVID-19 pandemic in the United States
1. This multicenter cohort study of 3922 children with Kawasaki disease (KD) demonstrated that...
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Vitamin and mineral supplementation associated with minimal to no benefit in the primary preventing of cardiovascular disease and cancer – US Preventative Services Task Force
1. Vitamin and mineral supplementation was associated with minimal to no benefit in preventing...
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Gut microbiota signatures of long-term and short-term plant-based dietary pattern and cardiometabolic health
1. Long-term plant-based diet was associated with more variance in microbial structure and future...
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Circulating Tumour DNA Analysis reduced adjuvant chemotherapy use while not compromising recurrence-free survival in stage II colon cancer
1. The circulating tumour DNA-guided approach was non-inferior to the standard clinicopathological...
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Social risk factors associated with increased pediatric emergency department utilization
1. In a large cohort of children screened for risk factors such as food insecurity and housing...
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