Elevated neutrophil-lymphocyte ratio associated with poor prognosis for head and neck cancer
1. This single-centred, observational cohort study demonstrated that among patients with head and...
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chronic-disease
Prenatal exposure to maternal autoimmune diseases associated with increased risks of mental disorders in offspring
1. In utero exposure to any maternal autoimmune disease was associated with increased risks of...
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Radiofrequency renal denervation produces long-lasting reductions in blood pressure
1. The intervention group saw a 10 mmHg greater reduction in 24-h mean systolic blood pressure...
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Reduced bleeding risk with asundexian compared to apixaban in patients with atrial fibrillation
1. Asundexian 50 mg resulted in a lower rate of bleeding compared to apixaban 5 mg twice daily. 2....
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Exposure to hydraulic fracturing sites is associated with some adverse birth outcomes
1. In a large cohort comparing 35,000 pregnancies of women living near hydraulic fracturing sites...
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Testing for sexually transmitted infections is infrequent among high school students in the United States
1. In a 2019 national survey of 2501 high school students across the United States, only 20.4% of...
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Adjuvant chemotherapy associated with an improved overall survival for patients with locally advanced gastric cancer
1. In this retrospective cohort study, 462 patients with locally advanced gastric cancer...
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Daprodustat noninferior to darbepoetin alfa in the treatment of anemia in patients with chronic kidney disease on incident dialysis – the ASCEND-ID trial
1. This trial demonstrated noninferiority of daprodustat to darbepoetin alfa in the treatment of...
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Presence of second midwife during the second active stage of labour reduces the risk of severe perineal trauma
1. Severe perineal trauma occurred in 5.7% of patients with one midwife and 3.9% of patients with...
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Subcortical neurons associated with sleep disturbances in neurodegenerative disease
1. Greater number of neurons in the lateral hypothalamic area (LHA) and tuberomammillary nucleus...
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Glyburide non-inferior to insulin for perinatal outcomes in gestational diabetes
1. This population-based cohort study demonstrated that oral glyburide as first-line treatment for...
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Bone mineral density testing beneficial for older men receiving androgen deprivation therapy for localized or regional prostate cancer
1. Bone mineral density testing was associated with a significant decreased risk of developing...
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Oral gefapixant reduces frequency of refractory or unexplained chronic coughs
1. Gefapixant 45 mg twice a day showed significant reductions in chronic cough over 12-24 weeks...
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Barriers to medication access for opioid use disorder in adolescents and young adults
1. In this systematic review of 37 studies, multiple barriers were identified in accessing...
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Obesity may be associated with better response to immune checkpoint blockade therapy
1. In this study, patients who were obese or overweight had better survival compared to normal...
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No difference in outcomes between 3 minimally invasive surgical procedures for treatment of lumbar spinal stenosis
1. In this randomized clinical trial of 437 patients, no significant difference was observed in...
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Rapid antigen tests detect high SARS-CoV-2 levels during the Omicron surge
1. Rapid antigen tests detected persons with high SARS-CoV-2 levels, enabling rapid response to...
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Examining associations between physical activity and the risk of disabling dementia in older adults
1. This large, prospective cohort study from Japan demonstrated an inverse association between the...
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Cessation of aspirin in older adults not associated with adverse health effects
1. Aspirin cessation in older adults led to increased cardiovascular disease events, though not...
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Changes in opioid or nonopioid pain treatments not attributable to state opioid prescribing laws
1. No changes in opioid or nonopioid pain prescribing patterns were attributable to state laws. 2....
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