Increased risk of intracranial hemorrhage with aspirin and unfractionated heparin use for endovascular stroke treatment
1. Ischemic stroke patients assigned to aspirin-only, heparin-only, or both, had worse Modified...
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chronic-disease
Valoctocogene roxaparvovec gene therapy efficacious for hemophilia A treatment
1. The adeno-associated virus 5 (AAV5)-based gene therapy, valoctocogene roxaparvovec...
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Iberdomide elicits SRI-4 response in patients with systemic lupus erythematosus
1. More patients with systemic lupus erythematosus (SLE) who received high doses of iberdomide...
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Hospitalized Covid-19 patients from socially vulnerable neighborhoods have greater illness severity
1. Hospitalized Covid-19 patients presenting from socially vulnerable neighborhoods had greater...
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Overdoses in youth with benzodiazepine and stimulant prescriptions
1. A retrospective analysis found that 29% of youth with benzodiazepine overdose and 25% of youth...
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Systematic review and meta-analysis of statin-induced reduction in LDL-C demonstrates modest absolute benefits
1. This systematic review and meta-analysis found a modest absolute risk reduction of 0.8% in...
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Non-severe tuberculosis in children can be treated with a shorter 4-month regimen
1. For children with non-severe tuberculosis, 4 months of antituberculosis treatments was...
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Low- and no-calorie sweetened beverages associated with reduced body weight compared to sugar-sweetened beverages: a systematic review and meta-analysis
1. This systematic review and meta-analysis demonstrated that low- and no-calorie sweetened...
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Garadacimab significantly reduces frequency of hereditary angioedema exacerbations
1. Garadacimab significantly reduced the number of monthly attacks in patients with hereditary...
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Early intervention services for children exposed to lead associated with improved standardized test performance
1. In a retrospective cohort of about 11,000 children with at least one blood lead level above 4...
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Effectiveness of Covid-19 vaccines waned over timer in North Carolina
1. Three Covid-19 vaccines from Pfizer, Moderna, and Johnson & Johnson provided durable...
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Maternal substance use may increase risk of childhood Attention Deficit Hyperactivity Disorder
1. Substance use in the prenatal period may be associated with an increased risk of an Attention...
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Majority of long-acting injectable and oral antipsychotics are similar in efficacy for schizophrenia maintenance therapy
1. There was no evidence of superiority among the different antipsychotics. 2. Choice of...
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Postoperative treatment without radioiodine has noninferior outcomes following thyroidectomy
1. Patients with low-risk thyroid cancer undergoing thyroidectomy, who did not receive radioiodine...
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Computed tomography a suitable diagnostic alternative for obstructive coronary artery disease
1. For patients referred for potential obstructive coronary artery disease (CAD), computed...
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Pro-inflammatory diets may objectively negatively impact sleep amongst police officers
1. This study showed that more pro-inflammatory diets led to higher wake-after-sleep-onset (WASO)...
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Combination treatment with varenicline and nicotine patch improves smoking cessation outcomes for concurrent alcohol users
1. In this randomized controlled trial, combined treatment with varenicline and nicotine patch...
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Melioidosis outbreak is associated with imported aromatherapy spray
1. Melioidosis, caused by Burkholderia pseudomallei, is rarely diagnosed in the US, and patients...
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Reliever-triggered inhaled glucocorticoid therapy in among Black and Latinx adults with asthma
1. Provision of an inhaled glucocorticoid and instruction on its use led to a significantly lower...
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Faricimab noninferior to aflibercept for treatment of neovascular age-related macular degeneration
1. In both trials, faricimab was demonstrated to be non-inferior to aflibercept at improving...
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