Clinically important troponin I threshold for mortality after cardiac surgery
1. For patients undergoing only a coronary-artery bypass grafting (CABG) or aortic-valve...
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chronic-disease
Intensive blood pressure control associated with increased cerebral blood flow in patients with hypertension – the SPRINT trial
1. In patients with hypertension, intensive blood pressure control to a target of less than 120...
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Faricimab may improve visual acuity in patients with diabetic macular edema
1. Faricimab every 8 weeks and faricimab per personalized treatment interval (PTI) were...
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2 Minute Medicine Rewind March 7, 2022
Association between Treatment for Localized Prostate Cancer and Mental Health Outcomes 1. No...
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Prophylactic nirsevimab protects infants from respiratory syncytial virus infection
1. Single-dose intramuscular injection of nirsevimab significantly reduced respiratory syncytial...
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AD26.COV2.S vaccine provides protection against Covid-19
1. The AD26.COV2.S vaccine provided protection against moderate to severe-critical Covid-19. 2....
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Concussions associated with adverse mental health outcomes in children
1. A large, retrospective population-based cohort study of over 150, 000 participants found an...
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Higher body mass index associated with improved cystic fibrosis-related clinical outcomes
1. This systematic review and meta-analysis demonstrated that higher-than-normal body mass index...
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Novavax vaccine is safe and effective for prevention of Covid-19
1. The Novavax vaccine provided high efficacy for the prevention of Covid-19. 2. The Novavax...
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Treatment of rhythmic and periodic EEG patterns in comatose survivors of cardiac arrest
1. For comatose survivors of cardiac arrest, treatment of rhythmic and periodic EEG activity did...
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COVID-19 vaccination and infection-acquired immunity provide protection against SARS-CoV-2 infection
1. Two doses of Pfizer-BioNTech vaccine were associated with short-term protection against...
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Discharge from pediatric intensive care unit after respiratory failure may be associated with long-term impact on neurocognition
1. Patients who were discharged from a pediatric intensive care unit for respiratory failure were...
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Congenital Zika syndrome is associated with higher risk of death
1. Children with congenital Zika syndrome had a higher risk of death throughout the first 3 years...
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S-1 plus oxaliplatin noninferior to fluorouracil, leucovorin, and oxaliplatin in perioperative chemotherapy for locally advanced gastric cancer: FOCUS trial
1. This phase 3, randomized controlled trial demonstrated that S-1 plus oxaliplatin (SOX) was...
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Peanut oral immunotherapy desensitizes young children with non-anaphylactic peanut allergies
1. Compared to placebo, children who received peanut oral immunotherapy experienced significantly...
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LentiGlobin efficacious for sickle cell disease hemolysis and vaso-occlusion
1. LentiGlobin gene therapy resulted in sustained production of the modified anti-sickling...
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Addition of atezolizumab to capecitabine + bevacizumab is not clinically beneficial in the treatment of refractory metastatic colorectal cancer
1. Atezolizumab plus capecitabine + bevacizumab performed marginally better with regards to...
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Chemotherapy not associated with an increased COVID-19 mortality risk in active cancer patients
1. This prospective cohort study demonstrated that, in adult patients with active cancer and a...
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Three-step support strategy reduces prolonged grief in relatives after death of intensive care unit patients
1. Grief measured at 6 months following the patient’s death was significantly lower in relatives...
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COVID-19 increased mortality disaster in Switzerland, Sweden, and Spain
1. COVID-19 caused the second-largest infection-related mortality disaster in Switzerland, Sweden,...
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