Bimekizumab Safe and Effective for Moderate-To-Severe Hidradenitis Suppurativa Treatment
1. Significantly more patients in the bimekizumab group than placebo reported improved clinical...
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chronic-disease
Long-term survival improved with use of tebentafusp for metastatic uveal melanoma
1. Across a median follow-up of 48.5 months, usage of tebentafusp for patients with metastatic...
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Gene Editing Improves Photoreceptor Function in Centrosomal Protein 290-Associated Retinal Degeneration
1. In this randomized controlled trial, among patients with centrosomal protein 290...
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Olezarsen effectively lowers triglycerides in patients with familial chylomicronemia syndrome
1. In this randomized controlled trial, 80 mg of olezarsen, but not 50 mg, significantly reduced...
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Aficamten improves oxygen uptake in patients with obstructive hypertrophic cardiomyopathy
1. In this randomized controlled trial, aficamten significantly improved peak oxygen uptake in...
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Bariatric surgery may improve rates for spontaneous ovulation in patients with polycystic ovarian syndrome and obesity
1. Women in the surgical group reported 2.5 times more spontaneous ovulations than in medical...
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Tofacitinib May Be Effective Pediatric Ulcerative Colitis Treatment
1. Management of pediatric ulcerative colitis with tofacitinib successfully induced...
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Olezarsen effectively decreases triglyceride levels
1. In this randomized controlled trial, in patients with hypertriglyceridemia and elevated...
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Long-term calcium and vitamin D supplementation does not impact all-cause mortality
1. In this randomized controlled trial, long-term calcium and vitamin D (CaD) supplementation was...
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Zodasiran associated with reduced triglyceride levels among adults with mixed hyperlipidemia
1. In this randomized controlled trial, adults with mixed hyperlipidemia who received zodasiran...
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Prophylactic therapy with recombinant ADAMTS13 safe for congenital TTP
1. In this randomized controlled trial, among individuals with congenital thrombotic...
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Asciminib demonstrates superior efficacy for the treatment of CML in comparison to imatinib and second-generation TKIs
1. Asciminib demonstrated higher efficacy for the treatment of newly diagnosed CML than imatinib...
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Mortality disparities recorded within Hispanic/Latino groups pre-pandemic
1. In this cohort study, within the pre-pandemic period, persons of Puerto Rican and Cuban...
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Neoadjuvant Nivolumab and Ipilimumab in Resectable Stage III Melanoma
1. The event-free survival at 12 months was 83.7% in the neoadjuvant group vs 57.2% in the...
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No benefit to fractional flow reserved-guided revascularization in myocardial infarction
1. In this randomized controlled trial, compared to culprit-lesion-only percutaneous coronary...
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SGLT2 inhibitors improved outcomes in stage five chronic kidney disease
1. In this retrospective cohort study, among patients with type 2 diabetes (T2D) and stage five...
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Empagliflozin does not decrease risk of hospitalization or death after myocardial infarction
1. In this randomized controlled trial, empagliflozin was not shown to decrease the risk of...
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Corticosteroid injections not found to be associated with fracture risk in elderly cohort
1. In a cohort of older adults, the use of corticosteroid injections (CSIs) was not associated...
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Vaping Associated With Increased Incidence of Respiratory Symptoms in Adolescents
1. In this retrospective analysis, compared to nonsmokers, vaping (both within the previous month...
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Albuminuria Within High Normal Range Increases Risk of Disease Progression in Patients With CKD
1. In this prospective cohort study involving patients with chronic kidney disease (CKD), those...
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