Daratumumab linked to improved progression-free survival and MRD-negativity in transplant-eligible myeloma patients
1. Daratumumab in combination with bortezomib, thalidomide, and dexamethasone (D-VTd) as induction...
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chronic-disease
Circulating Tumor DNA-Guided De-Escalation Targeted Therapy for Advanced NSCLC
1. Patients with no biochemical or radiographic evidence of progressive disease had a median...
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Ticagrelor and aspiring dual antiplatelet therapy is favourable over monotherapy following coronary artery bypass
1. Dual antiplatelet therapy with ticagrelor and asprin led to a significantly lower risk of major...
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Heat-Induced 1.5°C Core Temperature Increase Doubles Myocardial Blood Flow in Healthy Individuals; Linked to Asymptomatic Myocardial Ischemia in CAD
1. In this randomized controlled trial, exposure to heat that increased core temperature by 1.5C...
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Early asthma and COPD intervention decreases healthcare utilization
1. In this randomized controlled trial, adults with undiagnosed asthma or chronic obstructive...
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#VisualAbstract: Neoadjuvant Nivolumab and Ipilimumab Improve Outcomes in Resectable Stage III Melanoma
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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Osimertinib significantly improved progression-free survival in patients with unresectable stage III non-small cell lung cancer
1. Treatment with osimertinib significantly improved progression-free survival, compared to...
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Neoadjuvant Immunotherapy in Mismatch Repair–Deficient Colon Cancer
1. No disease recurrences were observed during the median follow-up time of 26.2 months. 2....
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Quantifying the reduction of primary breast cancer associated with exercise
1. Across a follow-up period of approximately 5 years, there was a non-linear relationship between...
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Telephone coaching program may help patients achieve weight loss
1. The addition of 3 or 12 weeks of telephone coaching for individuals with suboptimal response in...
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Bimekizumab Safe and Effective for Moderate-To-Severe Hidradenitis Suppurativa Treatment
1. Significantly more patients in the bimekizumab group than placebo reported improved clinical...
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Long-term survival improved with use of tebentafusp for metastatic uveal melanoma
1. Across a median follow-up of 48.5 months, usage of tebentafusp for patients with metastatic...
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Gene Editing Improves Photoreceptor Function in Centrosomal Protein 290-Associated Retinal Degeneration
1. In this randomized controlled trial, among patients with centrosomal protein 290...
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Olezarsen effectively lowers triglycerides in patients with familial chylomicronemia syndrome
1. In this randomized controlled trial, 80 mg of olezarsen, but not 50 mg, significantly reduced...
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Aficamten improves oxygen uptake in patients with obstructive hypertrophic cardiomyopathy
1. In this randomized controlled trial, aficamten significantly improved peak oxygen uptake in...
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Bariatric surgery may improve rates for spontaneous ovulation in patients with polycystic ovarian syndrome and obesity
1. Women in the surgical group reported 2.5 times more spontaneous ovulations than in medical...
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Tofacitinib May Be Effective Pediatric Ulcerative Colitis Treatment
1. Management of pediatric ulcerative colitis with tofacitinib successfully induced...
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Olezarsen effectively decreases triglyceride levels
1. In this randomized controlled trial, in patients with hypertriglyceridemia and elevated...
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Long-term calcium and vitamin D supplementation does not impact all-cause mortality
1. In this randomized controlled trial, long-term calcium and vitamin D (CaD) supplementation was...
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Zodasiran associated with reduced triglyceride levels among adults with mixed hyperlipidemia
1. In this randomized controlled trial, adults with mixed hyperlipidemia who received zodasiran...
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