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Critical Care General

Mechanistic Insights into the Oxidized Low-Density Lipoprotein-Induced Atherosclerosis.

Oct 08, 2020

Dyslipidaemia has a prominent role in the onset of notorious atherosclerosis, a disease of medium to large arteries. Atherosclerosis is the prime root of cardiovascular events contributing to the most...

Predictive value of sirtuins in acute myocardial infarction - Bridging the bench to the clinical practice.

Oct 08, 2020

Acute myocardial infarction (AMI) is a non-transmissible condition with high prevalence, morbidity, and mortality. Different strategies for the management of AMI are employed worldwide, but its early ...

Microcirculatory, Endothelial and Inflammatory Responses in Critically Ill Patients with COVID-19 are Distinct from those Seen in Septic Shock: A Case Control Study.

Oct 08, 2020

Critically ill patients with COVID-19 infection frequently exhibit a hyperinflammatory response and develop organ failures, however the underlying mechanisms are unclear. We investigated the microcirc...

The SPaCE diagnostic: a pilot study to test the accuracy of a novel point of care sensor for point of care detection of burn wound infection.

Oct 08, 2020

Wound infection in burn patients is common and impacts outcomes. There is no objective method to diagnose infection at point of care (PoC). Early diagnosis prevents progression to sepsis. Diagnostic s...

Targeting acute kidney injury in COVID-19.

Oct 08, 2020

As of 15 August 2020, Coronavirus disease 2019 (COVID-19) has been reported in >21 million people world-wide and is responsible for more than 750,000 deaths. The occurrence of acute kidney injury (...

Personalized Web-Based Cognitive Rehabilitation Treatments for Patients with Traumatic Brain Injury: Cluster Analysis.

Oct 08, 2020

Traumatic brain injury (TBI) is a leading cause of disability worldwide. TBI is a highly heterogeneous disease, which makes it complex for effective therapeutic interventions. Cluster analysis has bee...

Seeded laser-induced cavitation for studying high-strain-rate irreversible deformation of soft materials.

Oct 08, 2020

Characterizing the high-strain-rate and high-strain mechanics of soft materials is critical to understanding the complex behavior of polymers and various dynamic injury mechanisms, including traumatic...

The Brain Injury Functional Outcome Measure (BI-FOM): A single instrument capturing the range of recovery in moderate-severe traumatic brain injury.

Oct 08, 2020

To develop a measure of global functioning after moderate-severe TBI with similar measurement precision but a longer measurement range than the FIM.Phase 1: Retrospective analysis of 5 data sets conta...

Interatrial Block Predicts Atrial Fibrillation and Total Mortality in Patients with Cardiac Resynchronization Therapy.

Oct 08, 2020

Interatrial block (IAB) and abnormal P-wave terminal force in lead V1 (PTFV1) are electrocardiographic (ECG) abnormalities that have been shown to be associated with new-onset atrial fibrillation (AF)...

Usefulness of Peritoneal Ultrafiltration in Patients with Diuretic Resistant Heart Failure without End-Stage Renal Disease.

Oct 08, 2020

This study aimed to explore the role of peritoneal ultrafiltration (UF) in cardiorenal syndrome (CRS) patients for fluid and metabolic control.Peritoneal UF is safely and efficiently used for the mana...

Healthcare Utilization and Cost in Patients with Atrial Fibrillation and Heart Failure Undergoing Catheter Ablation.

Oct 08, 2020

Catheter ablation is an effective treatment for patients with atrial fibrillation (AF) and heart failure (HF). However, little is known how healthcare utilization and cost change after ablation in thi...

The presence of leukoaraiosis enhances the association between sTWEAK and hemorrhagic transformation.

Oct 08, 2020

To investigate whether elevated serum levels of sTWEAK (soluble tumor necrosis factor-like inducer of apoptosis) might be involved in a higher frequency of symptomatic hemorrhagic transformation (HT) ...

Ischemic Stroke: process perspective, clinical and profile characteristics, and external factors.

Oct 05, 2020

To describe a method of analysis for understanding the health care process, enriched with information on the clinical and profile characteristics of the patients. To apply the proposed technique to an...

GPR120 Ameliorates Apoptosis and Inhibits the Production of Inflammatory Cytokines in Renal Tubular Epithelial Cells.

Oct 05, 2020

Acute kidney injury (AKI) is the most common complication of sepsis with a high mortality rate. In this study, we focus on the renal injury caused by the immune response of renal tubular epithelial ce...

Human placenta-derived matrix with cancellous autograft and demineralized bone matrix for large segmental long-bone defects in two dogs with septic nonunion.

Oct 05, 2020

To report the successful treatment of septic nonunion in two dogs with large segmental defects secondary to long-bone fractures by using a novel human placenta-derived matrix (hPM) as adjunct to fixat...

Therapeutics on the clock: Circadian medicine in the treatment of chronic inflammatory diseases.

Oct 05, 2020

The circadian clock is a collection of endogenous oscillators with a periodicity of ∼24 hours. Recently, our understanding of circadian rhythms and their regulation at genomic and physiologic scales...

Fatal Invasive Pulmonary Aspergillosis in COVID-19 Patient with Acute Myeloid Leukemia in Iran.

Oct 05, 2020

Although patients with severe immunodeficiency and hematological malignancies has been considered at highest risk for invasive fungal infection, patients with severe pneumonia due to influenza, and se...

Recommendations for antibacterial therapy in adults with COVID-19 - An evidence based guideline.

Oct 05, 2020

The Dutch Working Party on Antibiotic Policy constituted a multidisciplinary expert committee to provide evidence-based recommendation for the use of antibacterial therapy in hospitalized adults with ...

Clonal spread of macrolide-resistant Mycoplasma pneumoniae sequence type-3 and type-17 with recombination on non-P1 adhesin among children in Taiwan.

Oct 05, 2020

Mycoplasma pneumoniae is currently the most commonly detected bacterial cause of childhood community-acquired pneumonia in several countries. Of note, clonal expansion of macrolide-resistant ST3 occur...

SOS Teeth: First Priority Teeth with Advanced Caries and Its Associations with Metabolic Syndrome among a National Representative Sample of Young and Middle-Aged Adults.

Oct 05, 2020

"SOS teeth" are defined as the first priority teeth for treatment, that have distinct cavitation reaching the pulp chamber or only root fragments are present. These are teeth with severe morbidity, th...

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