Aug 06, 2020

Estimated glomerular filtration rate (GFR) from cystatin C (eGFRcys) is often considered a more accurate method to assess GFR compared to estimated GFR from creatinine (eGFRcr) in the setting of heart...

Aug 06, 2020

Left ventricular hypertrophy (LVH) is an adaptive structural remodelling consequent to uncontrolled blood pressure. Impaired angiogenesis plays a vital role in transiting LVH into cardiac failure. Cat...

Aug 06, 2020

Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, has been declared by the WHO as an emerging public health problem of global importance and classified as a pandemic. SARS-CoV-2 inf...

Aug 06, 2020

Elevated left ventricular filling pressure (measured as mean pulmonary capillary wedge pressure, PCWPm) at rest or with exercise is diagnostic of heart failure with preserved ejection fraction (HFpEF)...

Aug 06, 2020

Atopic dermatitis (AD) has been linked to systemic infections in adulthood, but large-scale studies are few and potential associations unclear.To examine whether adults with AD have increased risk of ...

Aug 03, 2020

Ruxolitinib, a selective Janus kinase (JAK)1/2 inhibitor, has recently been proposed for steroid refractory chronic graft-versus host disease (cGVHD) after allogeneic hematopoietic stem cell transplan...

Aug 03, 2020

Endothelial cells lining the microvasculature are particularly vulnerable to the deleterious effects of cardiac ischemia/reperfusion (I/R) injury, a susceptibility that is partially mediated by dysreg...

Aug 03, 2020

The dysfunction of vascular endothelial cells is associated with sepsis development. Long noncoding RNAs take part in the regulation of vascular endothelial cell function. This study aimed to explore ...

Aug 03, 2020

Resection of the distal interphalangeal joint (DIJ) is a claw-preserving method for treatment of septic arthritis. This study presents the radiographic and histological findings of the surgically-trea...

Aug 03, 2020

The aim is to provide a narrative review of the role of corticosteroids, with and without inhaled beta agonist, in communityacquired pneumonia. Community and health-care associated pneumonia remain le...

Aug 03, 2020

The goal of this study was to assess chest computed tomography (CT) diagnostic accuracy in clinical practice using RT-PCR as standard of reference.From March 4th to April 9th 2020, during the peak of ...

Aug 03, 2020

The outbreak of the new coronavirus pneumonia (NCP) in Wuhan, Hubei, has caused very serious consequences and severely affected people's lives and mental health. The outbreak will cause bad emotions s...

Aug 03, 2020

Infection is postulated as a possible risk factor for ischemic heart disease with a spiralling body of evidence. Hepatitis B is one of the most comprehensively investigated infection for its associati...

Aug 03, 2020

Elective percutaneous coronary intervention (PCI) has become an increasingly safe procedure. However, same day discharge (SDD) has yet to become standard practice. Our aim is to characterize the patie...

Aug 03, 2020

This multi-institutional study compares the long-term outcome of elderly patients with severe aortic stenosis and an intermediate risk profile undergoing sutureless versus transcatheter aortic valve i...

Aug 03, 2020

Due to the high incidence and mortality of sepsis-associated acute kidney injury, a significant number of studies have explored the causes of sepsis-associated acute kidney injury (AKI). However, the ...

Aug 03, 2020

Extended early antibiotic exposure in the neonatal intensive care unit is associated with an increased risk for the development of late-onset sepsis (LOS). However, few studies have examined the mecha...

Aug 03, 2020

Innate immune cells, epithelial cells, and many other cell types are capable of detecting infection or tissue injury, thus mounting regulated immune response. Inflammasomes are highly sophisticated an...

Aug 03, 2020

Traumatic brain injury (TBI) induces inflammatory responses through microglial activation and polarization towards a more inflammatory state that contributes to the deleterious secondary brain injury....

Aug 03, 2020

In response to the need to better define the natural history of emerging consciousness after traumatic brain injury (TBI) and to better describe the characteristics of the condition commonly labeled P...