Jul 27, 2020

Following major trauma, sepsis or surgery, some patients exhibit an impaired monocyte inflammatory response that is characterized by a decreased response to a subsequent bacterial challenge. To invest...

Jul 27, 2020

Bloodstream infection and sepsis are major causes of health loss worldwide, and it is important to identify patients at risk of developing and dying from these conditions. The single-nucleotide polymo...

Jul 27, 2020

Efforts to reduce unnecessary antibiotic prescribing have coincided with increasing awareness of sepsis. We aimed to estimate the probability of sepsis following infection consultations in primary car...

Jul 27, 2020

Large-scale studies are required to better characterise traumatic brain injury (TBI) and to identify the most effective treatment approaches for TBI. However, evidence is scarce and mostly originates ...

Jul 27, 2020

To evaluate the effect of cognitive and physical rest on persistent post-concussive symptoms (PPCS) in a pediatric population.A prospective cohort study of 5-18-year-olds diagnosed with an acute concu...

Jul 27, 2020

Studies suggest that concussions may be related to increased risk of neurodegenerative diseases, such as Chronic Traumatic Encephalopathy and Alzheimer's Disease. Most neuroimaging studies show effect...

Jul 27, 2020

Evidence-based studies on endovascular approaches for childhood Takayasu arteritis(c-TA) are limited. This study presents the largest real-world scenario up-to-date for c-TA patients undergoing interv...

Jul 27, 2020

Heart failure (HF) causes pathological changes in multiple organs, thus affecting the pharmacokinetics of drugs. The aim of this study was to investigate the pharmacokinetics of candesartan in HF pati...

Jul 27, 2020

Anemia is very common in critical care patients, on admission (affecting about two-thirds of patients), but also during and after their stay, due to repeated blood loss, the effects of inflammation on...

Jul 27, 2020

This study sought to determine the impact of baseline chronic kidney disease (CKD) on in-hospital outcomes of transcatheter mitral valve repair with MitraClip (MC).MC is now an established treatment i...

Jul 27, 2020

The influence of specific brain lesions on health-related quality of life (HRQoL) after acute ischemic stroke (AIS) is uncertain. We aimed to identify imaging predictors of poor HRQoL in alteplase-tre...

Jul 23, 2020

Among diseases that cause small bowel obstruction, internal hernia may result in severe outcomes. Therefore, emergency laparotomy has been often performed, but it may be invasive. We experienced a cas...

Jul 23, 2020

Cardiac arrest (CA) is the leading cause of death around the world. Survivors after CA and cardiopulmonary resuscitation (CPR) develop moderate to severe cognitive impairment up to 60% at 3 months. Ac...

Jul 23, 2020

Exaggerated release of proinflammatory mediators during sepsis contributes to inadequate vasodilatation and depressed myocardial contractility, which lead to development of shock and circulatory colla...

Jul 23, 2020

 Performing lumbar punctures (LP) in all clinically suspected neonatal sepsis, as per current recommendations, results in many "negative" LPs. LPs are not without their own risks. With the intention...

Jul 23, 2020

 Cancer and pregnancy are likely increasing; however, updated estimates are needed to optimally address the unique needs of this patient population. The study aims to estimate the prevalence of canc...

Jul 23, 2020

The majority of the children with SARS-CoV-2 infection present with respiratory symptoms, hence various chest imaging modalities have been used in the management. Knowledge about the radiological find...

Jul 23, 2020

Fungal infections are on the rise, since the imunocompromised population is increasing due to AIDS/HIV, organ transplant and chemotherapy. Many environmental and pathogenic fungi are able to accomplis...

Jul 23, 2020

The purpose of this study was to evaluate the effect of depression on health behavior among myocardial infarction (MI) survivors.This retrospective, cross-sectional study used publicly available 2015 ...

Jul 23, 2020

Surgeons must discuss the most severe surgical complications with their patients while making a treatment decision. However, it is unclear which complications patients deem most severe. This study aim...