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Critical Care General

Thymopentin improves the survival of septic mice by promoting the production of 15-deoxy-prostaglandin J2 and activating the PPARγ signaling pathway.

Jul 13, 2020

Sepsis, a systemic inflammatory response syndrome (SIRS) caused by infection, is a major public health concern with limited therapeutic options. Infection disturbs the homeostasis of host, resulting i...

Soccer Heading and Subclinical Neuropsychiatric Symptomatology in Professional Soccer Players.

Jul 13, 2020

To evaluate the association between post-concussive symptomatology and heading in professional soccer players, overcoming the bias of self-reported exposure, we evaluated several clinical neuropsychia...

Targeting higher levels of lactate in the post-injury period following traumatic brain injury.

Jul 13, 2020

Secondary traumatic brain injury (TBI) consequences continue multiple cascades of biochemical reactions caused by initial neurotrauma and one of the important pathogenetic processes is mitochondrial d...

Controlling nutritional status (CONUT) score is a predictive marker for patients with traumatic brain injury.

Jul 13, 2020

We designed this study to evaluate whether controlling nutritional status (CONUT) score was valuable in predicting outcome of patients with traumatic brain injury (TBI).Clinical and laboratory data of...

Probability of sinus rhythm conversion and maintenance in cardiac re-synchronization therapy patients with atrial fibrillation during 5-year follow-up.

Jul 13, 2020

There is a high prevalence of atrial fibrillation (AF) in patients with heart failure presented for cardiac resynchronization therapy (CRT). It remains unclear whether an atrial lead should be implant...

Management and outcomes of heart failure patients with CKD: experience from an inter-disciplinary clinic.

Jul 13, 2020

CKD-HF patients suffer excess hospitalization and mortality, often under-treated with life-prolonging medications due to fear of worsening renal function and hyperkalaemia. Yet, role of inter-discipli...

The long-term impact of peripheral cannulation for redo cardiac surgery.

Jul 13, 2020

Redo cardiac surgery carries an inherent risk for adverse short-term outcomes and worse long-term survival. Strategies to mitigate these risks have been numerous, including initiation of cardiopulmona...

Improving timely treatment with a stroke emergency map: The case of northern China.

Jul 13, 2020

The Chinese stroke emergency map (SEM) was implemented in 2017 to reduce prehospital and hospital delays for acute ischemic stroke (AIS) patients suitable for intravenous recombinant tissue plasminoge...

Differential effect of cardiac resynchronization therapy in patients with diabetes mellitus: a long-term retrospective cohort study.

Jul 13, 2020

Cardiac resynchronization therapy (CRT) has become an important therapy in patients with heart failure with reduced left ventricular ejection fraction (LVEF). The effect of diabetes on long-term outco...

Assessing the Association of Surface-Intermediate-Base Margin Score with Perioperative Outcomes and Parenchymal Volume Preserved during Partial Nephrectomy.

Jul 09, 2020

The present study aimed to compare the assessment of volume preservation and perioperative outcomes during partial nephrectomy (PN), according to the surface-intermediate-base (SIB) score.This prospec...

Distinct clinical characteristics and risk factors for mortality in female COVID-19 inpatients: a sex-stratified large-scale cohort study in Wuhan, China.

Jul 09, 2020

As the coronavirus disease 2019 (COVID-19) outbreak accelerates worldwide, it is highly significant to evaluate sex-specific clinical characteristics and outcomes, that may affect public health polici...

Comparison of Surgical Stabilization Time in Patients with Flail Chest.

Jul 09, 2020

 This study aimed to compare the clinical outcomes of early and late surgical stabilization of rib fractures (SSRFs) in patients with flail chest. A retrospective analysis was performed on patient...

Clinical observations in the very elderly patients with COVID-19 in Wuhan.

Jul 09, 2020

In December 2019, the outbreak of coronavirus disease 2019 (COVID-19) was initiated in Wuhan, now causing a worldwide pandemic. However, the experience in the very elderly patients is very limited, wh...

Cluedo - Source identification in a case of septicemia fatality caused by Capnocytophaga canimorsus.

Jul 09, 2020

The Gram negative pathogen Capnocytophaga canimorsus is a frequent commensal in the oral cavity of cats and dogs. Although the bacterium is generally considered harmless, infections in humans can occu...

Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses.

Jul 09, 2020

Difference in blood and peritoneal glucose (DBPG) is used in clinical practice to support a diagnosis of septic peritonitis in horses. It is inexpensive, easy and rapid to perform. The aim of this stu...

COVID-19 PICU guidelines: for high- and limited-resource settings.

Jul 09, 2020

Fewer children than adults have been affected by the COVID-19 pandemic, and the clinical manifestations are distinct from those of adults. Some children particularly those with acute or chronic comorb...

The extravasation of contrast as a predictor of cerebral hemorrhagic contusion expansion, poor neurological outcome and mortality after traumatic brain injury: A systematic review and meta-analysis.

Jul 09, 2020

The active extravasation of contrast on CT angiography (CTA) in primary intracerebral hemorrhages (ICH) is recognized as a predictive factor for ICH expansion, unfavorable outcomes and mortality. Howe...

Silymarin sex-dependently improves cognitive functions and alters TNF-α, BDNF, and glutamate in the hippocampus of mice with mild traumatic brain injury.

Jul 09, 2020

Mild traumatic brain injury (mTBI) is an important risk factor for cognitive impairment. Despite intense efforts to develop efficient treatments, the current therapies are not often effective and far ...

Incidence, risk factors, and effects on outcome of ventilator-associated pneumonia in patients with traumatic brain injury. Analysis of a large, multicenter, prospective, observational longitudinal study.

Jul 09, 2020

No large prospective data are available on ventilator-associated pneumonia (VAP) in patients with traumatic brain injury (TBI).To evaluate the incidence, timing and risk factors of VAP after TBI and i...

Results of the surgical management of acute limb ischemia in the nonagenarians.

Jul 09, 2020

The aging of the population leads us to treat older patients, in particular presenting with acute limb ischemia (ALI). However there has been little evaluation of this pathology in the nonagenarians. ...

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