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Critical Care General

Switch to direct anticoagulants and improved endothelial function in patients with chronic heart failure and atrial fibrillation.

Jul 09, 2020

Chronic heart failure (CHF) is characterized by higher rates of atrial fibrillation (AF) and endothelial dysfunction (ED). First line anticoagulant therapy in AF is represented by direct oral anticoag...

Characteristics of Effective Teachers of Invasive Bedside Procedures: A Multiinstitutional Qualitative Study.

Jul 09, 2020

Faculty supervision of invasive bedside procedures (IBPs) in the ICU may enhance procedural education and ensure patient safety. However, there is limited research on teaching effectiveness in the ICU...

COVID-19 and Stroke: Casual or Causal Role?

Jul 09, 2020

The COVID-19 outbreak is currently the major public health concern worldwide. This infection, caused by the novel coronavirus Sars Cov2, primarily affects respiratory system, but there is increasing e...

Association between male sex and outcomes of Coronavirus Disease 2019 (Covid-19) - a Danish nationwide, register-based study.

Jul 09, 2020

Male sex has been associated with severe Coronavirus disease 2019 (Covid-19) infection. We examined the association between male sex and severe Covid-19 infection and if an increased risk remains afte...

Effect of Haemophilus influenzae type b and 13-valent pneumococcal conjugate vaccines on childhood pneumonia hospitalizations and deaths in Botswana.

Jul 09, 2020

Globally, pneumonia is the leading cause of death among children. Few data exist regarding the effect of Haemophilus influenzae type b (Hib) vaccine and 13-valent pneumococcal conjugate vaccine (PCV-1...

Identifying Risk Factors for AKI in the Pediatric ICU

Jul 07, 2020

Data indicate that acute kidney injury (AKI) affects one-third of children admitted to a pediatric intensive care unit (PICU) and is related to the development of several complications and poor outcom...

Assessing MRSA Risk in the Surgical Intensive Care Unit: Who Warrants Empiric Therapy?

Jul 06, 2020

Data showing an increase in prevalence of MRSA and other multi-drug resistant organism (MDRO) infections in ICU patients suggests that antimicrobial resistance continues to increase in this population...

Projections of temperature-related cause-specific mortality under climate change scenarios in a coastal city of China.

Jul 06, 2020

Numerous studies have been conducted to project temperature-related mortality under climate change scenarios. However, most of the previous evidence has been limited to the total or non-accidental mor...

MiR-483-3p inhibition ameliorates myocardial ischemia/reperfusion injury by targeting the MDM4/p53 pathway.

Jul 06, 2020

MiR-483-3p is involved in the pathogenesis of acute myocardial infarctions, but its association with myocardial ischemia reperfusion (IR) remains mostly unknown. In this study, an in vitro model of my...

Extended endonasal endoscopic approach for anterior midline skull base lesions.

Jul 06, 2020

In recent years, extended endoscopic endonasal approach (EEEA) has been used as an alternative to transcranial approaches in the treatment of anterior midline skull base lesions. We retrospectively re...

Case reports study of the first five patients COVID-19 treated with remdesivir in France.

Jul 06, 2020

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been identified as responsible for the COVID-19 outbreak worldwide. Data on treatment are scare and parallels are made between SARS...

Chest-CT findings of COVID-19 in patients with pre-existing malignancies; a pictorial review.

Jul 06, 2020

As of April 17th, 2020, more than 2,190,010 COVID-19 cases with 147,010 deaths have been recorded worldwide. It has been suggested that a high mortality rate occurs in patients with severe disease and...

Nasogastric versus Orogastric Bolus Tube Feeding in Preterm Infants: Pilot Randomized Clinical Trial.

Jul 06, 2020

 According to the most recent metanalysis, the best way to establish safe enteral feeding in preterm babies using nasogastric or orogastric tubes is still not well understood. This study aimed to de...

Different contribution of SBP and DBP variability to vascular events in patients with stroke.

Jul 06, 2020

High blood pressure variability (BPV) is a novel risk factor for cardiovascular disease. However, the heterogeneity of systolic blood pressure variability (SBPV) and diastolic blood pressure variabili...

A Comparison of Sepsis-2 (Systemic Inflammatory Response Syndrome Based) to Sepsis-3 (Sequential Organ Failure Assessment Based) Definitions-A Multicenter Retrospective Study.

Jul 06, 2020

Recently, the definition of sepsis has changed from a physiologic derangement (Sepsis-1 and -2) to organ dysfunction (Sepsis-3) based. We sought to determine the concordance between the different seps...

species infections in humans: a systematic review.

Jul 06, 2020

species have been recognized to cause infections in immunocompromised individuals. The purpose of this study was to systemically review all published cases of infections in humans and describe the e...

Association of Trauma Center Level and Patient Volume with Outcomes for Penetrating Thoracic Trauma.

Jul 06, 2020

We investigated the potential link between trauma center American College of Surgeons verification level and institutional volume of penetrating thoracic trauma with outcomes for patients with penetra...

Characterizing Early Inpatient Death After Trauma.

Jul 06, 2020

There is a paucity of data to predict early death or futility after trauma. The objective of this study was to characterize the laboratory values, blood product administration, and hospital dispositio...

Surgical outcomes in traumatic brain injuries with bilateral mass occupying lesions. Analysis of prognostic factors.

Jul 06, 2020

Traumatic brain injury is a silent epidemic with major impacts on national productivity as it affects the economically productive age group. Bilateral injuries are usually severe with no clearly defin...

Long-term follow-up of neurosurgical outcomes for adult patients in Uganda with traumatic brain injury.

Jul 06, 2020

Traumatic brain injury (TBI) is a major cause of mortality and morbidity in Uganda and other low- and middle-income countries (LMICs). Due to the difficulty of long-term in-person follow-up, there is ...

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