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Critical Care General

Modulation of Startle and Heart Rate Responses by Fear of Physical Activity in Patients with Heart Failure and in Healthy Adults.

Jul 06, 2020

Fear of physical activity (FoPA) is prevalent in patients with heart failure and associated with lower physical activity despite medical exercise prescriptions. The present study examined physiologica...

Long-Term Implications of Tracheostomy in Cardiac Surgery Patients: Decannulation and Mortality.

Jul 06, 2020

The long-term implications of tracheostomy in cardiac surgical patients are largely unknown. We sought to investigate outcomes including decannulation and long-term mortality in a population of post-c...

Transvenous Phrenic Nerve Stimulation for Central Sleep Apnea is Safe and Effective in Patients with Concomitant Cardiac Devices.

Jul 06, 2020

Central sleep apnea is common in heart failure patients. Transvenous phrenic nerve stimulation (TPNS) requires placing a lead to stimulate the phrenic nerve and activate the diaphragm. Data are lackin...

Effect of Covid-19 pandemic on stroke admission rates in a Norwegian population.

Jul 06, 2020

There are concerns that public anxiety around Covid-19 discourages patients from seeking medical help. The aim of this study was to see how lockdown due to the pandemic affected the number of admissio...

The 5 and 11 Factor Modified Frailty Indices are Equally Effective at Outcome Prediction Using TQIP.

Jul 06, 2020

The 5-factor modified frailty index (mFI-5) and the 11-factor modified frailty index (mFI-11) are equally effective in predicting adverse outcomes in the American College of Surgeons National Surgical...

Automated stroke lesion segmentation in non-contrast CT scans using dense multi-path contextual generative adversarial network.

Jul 02, 2020

Stroke lesion volume is a key radiologic measurement in assessing prognosis of acute ischemic stroke (AIS) patients. The aim of this paper is to develop an automated segmentation method for accurately...

Trans-cranial Doppler predicts early neurologic deterioration in anterior circulation ischemic stroke after successful endovascular treatment.

Jul 02, 2020

Early neurologic deterioration (END) may occur in patients with anterior circulation ischemic stroke (ACIS) after receiving endovascular treatment (EVT). Hemodynamic insufficiency, re-occlusion, and p...

Diagnosing Calciphylaxis: A Review With Emphasis on Histopathology.

Jul 02, 2020

Calciphylaxis is a cutaneous vasculopathy with high morbidity and mortality characterized by vascular intimal fibrosis, calcification, stenosis, thrombosis, and eventual tissue death due to ischemia. ...

The Effect of Xinmailong Infusion on Sepsis-Induced Myocardial Dysfunction: A Pragmatic Randomized Controlled Trial.

Jul 02, 2020

Sepsis-induced myocardial dysfunction (SIMD) contributes significantly to cardiovascular dysfunction during septic shock. We aimed to evaluate the potential role of Xinmailong injection (XMLI), a poly...

Outcomes and Disposition of Oncology Patients With Non-neutropenic Fever and Positive Blood Cultures.

Jul 02, 2020

Children with cancer and non-neutropenic fever (NNF) episodes are often treated as outpatients if they appear well. However, a small subset have bloodstream infections (BSIs) and must return for furth...

Dose optimized chest CT for diagnosis of COVID-19 - Evaluation of the image quality and diagnostic impact.

Jul 02, 2020

The detection of COVID-19 by reverse transcription polymerase chain reaction (RT-PCR) has varying sensitivity. CT of the chest can verify the infection in patients with clinical symptoms and a negativ...

Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo'.

Jul 02, 2020

On the 21 of February 2020 a resident of the municipality of Vo', a small town near Padua, died of pneumonia due to SARS-CoV-2 infection. This was the first COVID-19 death detected in Italy since the ...

Iron imaging in myocardial infarction reperfusion injury.

Jul 02, 2020

Restoration of coronary blood flow after a heart attack can cause reperfusion injury potentially leading to impaired cardiac function, adverse tissue remodeling and heart failure. Iron is an essential...

External validation of the sepsis severity score.

Jul 02, 2020

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Mortality rates are high, exceeding 50% in patients with septic shock. The sepsis severit...

Elevated trefoil factor 3 plasma levels in critically ill patients with abdominal sepsis or non-infectious abdominal illness.

Jul 02, 2020

Trefoil factor 3 (TFF3) is a small peptide secreted mainly by goblet cells in the gut, where it plays a key role in gastrointestinal defence and repair. Plasma TFF3 has been reported as a biomarker of...

Therapeutic Potential of B-1a Cells in COVID-19.

Jul 02, 2020

Coronavirus disease 2019 (COVID-19) is a life-threatening respiratory illness caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Its clinical presentation can vary from ...

Proteomic changes by radio-mitigative thrombopoietin receptor agonist Romiplostim in the blood of mice exposed to lethal total-body irradiation.

Jul 02, 2020

The thrombopoietin receptor agonist romiplostim (RP) is a therapeutic agent for immune thrombocytopenia that can achieve complete survival in mice exposed to a lethal dose of ionizing radiation. The ...

The relationship between neurovascular coupling, vision and sensory performance, and concussion history in Special Operations Forces combat soldiers.

Jul 02, 2020

To determine the relationship between neurovascular coupling (NVC), vision and sensory performance in Special Operations Forces (SOF) combat soldiers with and without concussion history. We studied 6...

Fatal accident involving a welder employed by a shipping container company, associated with the use of tramadol and antidepressant agents.

Jul 02, 2020

The widespread use of opioids for the treatment of moderate or severe acute and chronic pain has become a public health problem due to the physical and psychological dependence and tolerance they prod...

His Bundle and Left Bundle Pacing with Optimised Atrio-ventricular Delay Achieve Superior Electrical Synchrony over Endocardial and Epicardial Pacing in Left Bundle Branch Block Patients.

Jul 02, 2020

His bundle pacing (HBP) and left bundle pacing (LBP) are emerging as novel delivery methods for cardiac resynchronisation therapy (CRT) in heart failure patients with left bundle branch block (LBBB). ...

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